There is a lack of knowledge on the possible influence of systemic conditions on peri-implantitis. The aim of this case-control study is to evaluate the difference in terms of oral patho-gens’ concentrations in the peri-implant sulcus of a group of patients affected by metabolic syndrome (Mets) compared to healthy subjects. For each patient, peri-implant sulcular biofilm samples were obtained by inserting two sterile endodontic paper points in the deepest aspect of the peri-implant sulcus for 30 s. The quantitative real-time polymerase chain reaction was performed to evaluate total bacterial counts of six pathogens. Patients were screened for peri-implant diseases and clinical and radiographic parameters were recorded. A total of 50 patients was enrolled in the study, 25 affected by Mets and 25 healthy. Significantly higher bacterial counts were discovered for Aggregatibacter Actinomycetemcomitans (p = 0.0008), Prevotella Intermedia (p = 0.0477) and Staphylococ-cus Aureus (p = 0.034) in MetS patients compared to healthy subjects. Performing a sub-group anal-ysis, considering peri-implant status and dividing patients by MetS diagnosis, no statistically sig-nificant (p < 0.05) differences were found. For the first time, a correlation between MetS presence and a greater prevalence of some bacterial species in the peri-implant sulcus was reported, irrespec-tively from peri-implant status (health vs disease).
Microbiological profiles of dental implants in metabolic syndrome patients: a case-control study / Di Murro, B.; Moretti, M.; De Smaele, E.; Letizia, C.; Lubrano, C.; Passarelli, P. C.; D'addona, A.; Pompa, G.; Papi, P.. - In: ANTIBIOTICS. - ISSN 2079-6382. - 10:4(2021). [10.3390/antibiotics10040452]
Microbiological profiles of dental implants in metabolic syndrome patients: a case-control study
Di Murro B.Primo
Investigation
;Moretti M.Secondo
Formal Analysis
;De Smaele E.Writing – Review & Editing
;Letizia C.Writing – Review & Editing
;Lubrano C.Writing – Review & Editing
;D'addona A.Writing – Review & Editing
;Pompa G.Penultimo
Writing – Review & Editing
;Papi P.
Ultimo
Conceptualization
2021
Abstract
There is a lack of knowledge on the possible influence of systemic conditions on peri-implantitis. The aim of this case-control study is to evaluate the difference in terms of oral patho-gens’ concentrations in the peri-implant sulcus of a group of patients affected by metabolic syndrome (Mets) compared to healthy subjects. For each patient, peri-implant sulcular biofilm samples were obtained by inserting two sterile endodontic paper points in the deepest aspect of the peri-implant sulcus for 30 s. The quantitative real-time polymerase chain reaction was performed to evaluate total bacterial counts of six pathogens. Patients were screened for peri-implant diseases and clinical and radiographic parameters were recorded. A total of 50 patients was enrolled in the study, 25 affected by Mets and 25 healthy. Significantly higher bacterial counts were discovered for Aggregatibacter Actinomycetemcomitans (p = 0.0008), Prevotella Intermedia (p = 0.0477) and Staphylococ-cus Aureus (p = 0.034) in MetS patients compared to healthy subjects. Performing a sub-group anal-ysis, considering peri-implant status and dividing patients by MetS diagnosis, no statistically sig-nificant (p < 0.05) differences were found. For the first time, a correlation between MetS presence and a greater prevalence of some bacterial species in the peri-implant sulcus was reported, irrespec-tively from peri-implant status (health vs disease).File | Dimensione | Formato | |
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