Multiple sclerosis is the leading nontraumatic cause of neurologic disability in young adults. The need to prevent neurodegeneration and promote repair in multiple sclerosis (MS) has gained increasing interest in the last decade leading to the search and development of pharmacological agents and non-pharmacologic strategies able to target not only the inflammatory but also the neurodegenerative component of the disease. This paper will provide an overview of the therapeutics currently employed in MS, with a focus on their potential neuroprotective effects and on the MRI methods employed to detect and monitor in-vivo neuroprotection and repair and the relevance of this information to schizophrenia investigation and treatment. (C) 2014 Elsevier B.V. All rights reserved.
Therapeutic strategies in multiple sclerosis: A focus on neuroprotection and repair and relevance to schizophrenia / Inglese, M; Petracca, M. - In: SCHIZOPHRENIA RESEARCH. - ISSN 0920-9964. - 161:1(2015), pp. 94-101. [10.1016/j.schres.2014.04.040.]
Therapeutic strategies in multiple sclerosis: A focus on neuroprotection and repair and relevance to schizophrenia
Petracca MUltimo
2015
Abstract
Multiple sclerosis is the leading nontraumatic cause of neurologic disability in young adults. The need to prevent neurodegeneration and promote repair in multiple sclerosis (MS) has gained increasing interest in the last decade leading to the search and development of pharmacological agents and non-pharmacologic strategies able to target not only the inflammatory but also the neurodegenerative component of the disease. This paper will provide an overview of the therapeutics currently employed in MS, with a focus on their potential neuroprotective effects and on the MRI methods employed to detect and monitor in-vivo neuroprotection and repair and the relevance of this information to schizophrenia investigation and treatment. (C) 2014 Elsevier B.V. All rights reserved.File | Dimensione | Formato | |
---|---|---|---|
Inglese_Therapeutic strategies in multiple sclerosis_2015.pdf
solo gestori archivio
Tipologia:
Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza:
Tutti i diritti riservati (All rights reserved)
Dimensione
269.24 kB
Formato
Adobe PDF
|
269.24 kB | Adobe PDF | Contatta l'autore |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.