The serum prostate-specific antigen is the most widespread biomarker for prostate disease. Its low specificity for prostatic malignancies is a matter of concern and the reason why new biomarkers for screening purposes are needed. The correlation between altered production of the main steroids and prostate carcinoma (PCa) occurrence is historically known. The purpose of this study is to evaluate the modifications of a comprehensive urinary endogenous steroidal profile (USP) induced by PCa, by multivariate statistical methods.

Prospective evaluation of urinary steroids and prostate carcinoma-induced deviation: preliminary results / DE Luca, Stefano; Amante, Eleonora; Fiori, Cristian; Alleva, Giorgio; Alladio, Eugenio; Marini, Federico; Garrou, Diletta; Manfredi, Matteo; Amparore, Daniele; Checcucci, Enrico; Pruner, Serena; Salomone, Alberto; Scarpa, Roberto M; Vincenti, Marco; Porpiglia, Francesco. - In: MINERVA UROLOGY AND NEPHROLOGY. - ISSN 2724-6442. - 73:1(2021), pp. 98-106. [10.23736/S0393-2249.19.03529-X]

Prospective evaluation of urinary steroids and prostate carcinoma-induced deviation: preliminary results

Marini, Federico;
2021

Abstract

The serum prostate-specific antigen is the most widespread biomarker for prostate disease. Its low specificity for prostatic malignancies is a matter of concern and the reason why new biomarkers for screening purposes are needed. The correlation between altered production of the main steroids and prostate carcinoma (PCa) occurrence is historically known. The purpose of this study is to evaluate the modifications of a comprehensive urinary endogenous steroidal profile (USP) induced by PCa, by multivariate statistical methods.
2021
Urine; Steroids; Prostatic neoplasms; Biomarkers; Gas chromatography-mass spectrometry
01 Pubblicazione su rivista::01a Articolo in rivista
Prospective evaluation of urinary steroids and prostate carcinoma-induced deviation: preliminary results / DE Luca, Stefano; Amante, Eleonora; Fiori, Cristian; Alleva, Giorgio; Alladio, Eugenio; Marini, Federico; Garrou, Diletta; Manfredi, Matteo; Amparore, Daniele; Checcucci, Enrico; Pruner, Serena; Salomone, Alberto; Scarpa, Roberto M; Vincenti, Marco; Porpiglia, Francesco. - In: MINERVA UROLOGY AND NEPHROLOGY. - ISSN 2724-6442. - 73:1(2021), pp. 98-106. [10.23736/S0393-2249.19.03529-X]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1544463
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