The immunity against poliomyelitis in 1000 subjects 13-14 years old was evaluated. Neutralizing antibodies against poliovirus type 1, 2 and 3 were detected in 97.6%, 95.8% and 70% of samples, respectively. 3/1000 (0.3%) subjects were simultaneously seronegative to the three types. WHO does not suggest a protective level of International Units (IU), but our data indicate that such level is 0.45 IU for polio type 1, 0.65 IU for the type 2 and 0.138 for the type 3. A booster dose of vaccine in adolescence to ensure personal and herd immunity is recommended.
Immunity status against poliomyelitis in persons 13-14 years old living in Rome / Mastroeni, I.; Patti, A. M.; Fabrizi, A.; Santi, A. L.; Manduca, A. M.; Vescia, N.; Squarcione, S.; Fara, G. M.. - In: VACCINE. - ISSN 0264-410X. - 15:6-7(1997), pp. 747-750. [10.1016/S0264-410X(96)00208-3]
Immunity status against poliomyelitis in persons 13-14 years old living in Rome
Mastroeni I.;Patti A. M.;Santi A. L.;Fara G. M.
1997
Abstract
The immunity against poliomyelitis in 1000 subjects 13-14 years old was evaluated. Neutralizing antibodies against poliovirus type 1, 2 and 3 were detected in 97.6%, 95.8% and 70% of samples, respectively. 3/1000 (0.3%) subjects were simultaneously seronegative to the three types. WHO does not suggest a protective level of International Units (IU), but our data indicate that such level is 0.45 IU for polio type 1, 0.65 IU for the type 2 and 0.138 for the type 3. A booster dose of vaccine in adolescence to ensure personal and herd immunity is recommended.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
