Accuracy of self-assessment of real-life functioning in schizophrenia

Rocca, P.; Brasso, C.; Montemagni, C.; Bellino, S.; Rossi, A.; Bertolino, A.; Gibertoni, D.; Aguglia, E.; Amore, M.; Andriola, I.; Bellomo, A.; Bucci, P.; Buzzanca, A.; Carpiniello, B.; Cuomo, A.; Dell'Osso, L.; Favaro, A.; Giordano, G. M.; Marchesi, C.; Monteleone, P.; Oldani, L.; Pompili, M.; Roncone, R.; Rossi, R.; Siracusano, A.; Vita, A.; Zeppegno, P.; Galderisi, S.; Maj, M.; Bozzatello, P.; Badino, C.; Giordano, B.; Di Palo, P.; Calia, V.; Papalino, M.; Barlati, S.; Deste, G.; Ceraso, A.; Pinna, F.; Olivieri, B.; Manca, D.; Piegari, G.; Brando, F.; Giuliani, L.; Aiello, C.; Poli, L. F.; Concerto, C.; Surace, T.; Altamura, M.; Malerba, S.; Padalino, F.; Calcagno, P.; Murri, M. B.; Amerio, A.; Pacitti, F.; Socci, V.; Lucaselli, A.; Giusti, L.; Salza, A.; Ussorio, D.; Iasevoli, F.; Gramaglia, C.; Gambaro, E.; Gattoni, E.; Tenconi, E.; Collantoni, E.; Meneguzzo, P.; Ossola, P.; Tonna, M.; Gerra, M. L.; Carmassi, C.; Carpita, B.; Cremone, I. M.; Corrivetti, G.; Cascino, G.; Marciello, F.; Brugnoli, R.; Comparelli, A.; Corigliano, V.; Girardi, N.; Accinni, T.; Carlone, L.; Fagiolini, A.; Goracci, A.; Bolognesi, S.; Di Lorenzo, G.; Niolu, C.; Ribolsi, M.

doi:10.1038/s41537-021-00140-9

A consensus has not yet been reached regarding the accuracy of people with schizophrenia in self-reporting their real-life functioning. In a large (n = 618) cohort of stable, community-dwelling schizophrenia patients we sought to: (1) examine the concordance of patients’ reports of their real-life functioning with the reports of their key caregiver; (2) identify which patient characteristics are associated to the differences between patients and informants. Patient-caregiver concordance of the ratings in three Specific Level of Functioning Scale (SLOF) domains (interpersonal relationships, everyday life skills, work skills) was evaluated with matched-pair t tests, the Lin’s concordance correlation, Somers’ D, and Bland–Altman plots with limits of agreement (LOA). Predictors of the patient-caregiver differences in SLOF ratings were assessed with a linear regression with multivariable fractional polynomials. Patients’ self-evaluation of functioning was higher than caregivers’ in all the evaluated domains of the SLOF and 17.6% of the patients exceeded the LOA, thus providing a self-evaluation discordant from their key caregivers. The strongest predictors of patient-caregiver discrepancies were caregivers’ ratings in each SLOF domain. In clinically stable outpatients with a moderate degree of functional impairment, self-evaluation with the SLOF scale can become a useful, informative and reliable clinical tool to design a tailored rehabilitation program.

Accuracy of self-assessment of real-life functioning in schizophrenia / Rocca, P.; Brasso, C.; Montemagni, C.; Bellino, S.; Rossi, A.; Bertolino, A.; Gibertoni, D.; Aguglia, E.; Amore, M.; Andriola, I.; Bellomo, A.; Bucci, P.; Buzzanca, A.; Carpiniello, B.; Cuomo, A.; Dell'Osso, L.; Favaro, A.; Giordano, G. M.; Marchesi, C.; Monteleone, P.; Oldani, L.; Pompili, M.; Roncone, R.; Rossi, R.; Siracusano, A.; Vita, A.; Zeppegno, P.; Galderisi, S.; Maj, M.; Bozzatello, P.; Badino, C.; Giordano, B.; Di Palo, P.; Calia, V.; Papalino, M.; Barlati, S.; Deste, G.; Ceraso, A.; Pinna, F.; Olivieri, B.; Manca, D.; Piegari, G.; Brando, F.; Giuliani, L.; Aiello, C.; Poli, L. F.; Concerto, C.; Surace, T.; Altamura, M.; Malerba, S.; Padalino, F.; Calcagno, P.; Murri, M. B.; Amerio, A.; Pacitti, F.; Socci, V.; Lucaselli, A.; Giusti, L.; Salza, A.; Ussorio, D.; Iasevoli, F.; Gramaglia, C.; Gambaro, E.; Gattoni, E.; Tenconi, E.; Collantoni, E.; Meneguzzo, P.; Ossola, P.; Tonna, M.; Gerra, M. L.; Carmassi, C.; Carpita, B.; Cremone, I. M.; Corrivetti, G.; Cascino, G.; Marciello, F.; Brugnoli, R.; Comparelli, A.; Corigliano, V.; Girardi, N.; Accinni, T.; Carlone, L.; Fagiolini, A.; Goracci, A.; Bolognesi, S.; Di Lorenzo, G.; Niolu, C.; Ribolsi, M.. - In: NPJ SCHIZOPHRENIA. - ISSN 2334-265X. - 7:1(2021), p. 11. [10.1038/s41537-021-00140-9]