Drug-Induced Brugada Syndrome in a Psychiatric Patient. a Case Report

Brugada syndrome is a hereditary arrhythmic disease characterized by the presence of coved ST elevation (at least 2 mm), with a negative T wave of the right precordial ECG leads (type 1 Brugada pattern). It is related to at least one of the following criteria: syncope or cardiac arrest, ventricular fibrillation or polymorphic ventricular tachycardia (documented or inducible), family history of type 1 Brugada pattern, sudden death before 45 years old, or nocturnal agonal respiration [1].Moreover, signs of Brugada syndrome have been found in asymptomatic patients exposed to certain drugs [2]. In this report, we describe the case of a 44-year-old woman with positive anamnesis for psychiatric drug use and recurrent syncopal episodes. There was no surface ECG and 24-h holter ECG monitoring and the ajmaline test were necessary to detect coved-type Brugada pattern