Nanosecond pulsed electric fields (nsPEFs) can interact with lipid vesicles, that are primary drug delivery nanocarriers activated by external signals. In this work, authors propose a new setup of an experimental bench suitable for nsPEFs exposure of liposome nanosystems, compliant with the wideband requirements for nanosecond pulses. A multiphysics modelling able to predict liposome poration is proposed to define the characteristics of signals to be used in experiments.
A coplanar waveguide system for drug delivery mediated by nanoelectroporation: an experimental and numerical study / Caramazza, Laura; Paffi, Alessandra; Liberti, Micaela; Apollonio, Francesca. - (2021), pp. 999-1002. (Intervento presentato al convegno 2020 50th European Microwave Conference (EuMC) tenutosi a Utrecht; Netherlands) [10.23919/EuMC48046.2021.9338023].
A coplanar waveguide system for drug delivery mediated by nanoelectroporation: an experimental and numerical study
Laura Caramazza
Primo
;Alessandra PaffiSecondo
;Micaela LibertiPenultimo
;Francesca ApollonioUltimo
2021
Abstract
Nanosecond pulsed electric fields (nsPEFs) can interact with lipid vesicles, that are primary drug delivery nanocarriers activated by external signals. In this work, authors propose a new setup of an experimental bench suitable for nsPEFs exposure of liposome nanosystems, compliant with the wideband requirements for nanosecond pulses. A multiphysics modelling able to predict liposome poration is proposed to define the characteristics of signals to be used in experiments.| File | Dimensione | Formato | |
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