The mutational status of stage III and IV melanomas should be recognized in order to allow for targeted therapies. The aim of our study was the characterization of BRAF, NRAS and C-KIT melanoma patients, in order to define their optimal management.

BRAF ,NRASandC-KITAdvanced Melanoma: Clinico-pathological Features, Targeted-Therapy Strategies and Survival / Ponti, Giovanni; Manfredini, Marco; Greco, Stefano; Pellacani, Giovanni; Depenni, Roberta; Tomasi, Aldo; Maccaferri, Monia; Cascinu, Stefano. - In: ANTICANCER RESEARCH. - ISSN 0250-7005. - 37:12(2017), pp. 7043-7048. [10.21873/anticanres.12175]

BRAF ,NRASandC-KITAdvanced Melanoma: Clinico-pathological Features, Targeted-Therapy Strategies and Survival

Pellacani, Giovanni;
2017

Abstract

The mutational status of stage III and IV melanomas should be recognized in order to allow for targeted therapies. The aim of our study was the characterization of BRAF, NRAS and C-KIT melanoma patients, in order to define their optimal management.
2017
Advanced melanoma; BRAF; NRAS and C-KIT; survival; targeted therapies; Aged; Antineoplastic Agents; Female; GTP Phosphohydrolases; Humans; Kaplan-Meier Estimate; Male; Melanoma; Membrane Proteins; Middle Aged; Molecular Targeted Therapy; Prognosis; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-kit; Skin Neoplasms; Mutation
01 Pubblicazione su rivista::01a Articolo in rivista
BRAF ,NRASandC-KITAdvanced Melanoma: Clinico-pathological Features, Targeted-Therapy Strategies and Survival / Ponti, Giovanni; Manfredini, Marco; Greco, Stefano; Pellacani, Giovanni; Depenni, Roberta; Tomasi, Aldo; Maccaferri, Monia; Cascinu, Stefano. - In: ANTICANCER RESEARCH. - ISSN 0250-7005. - 37:12(2017), pp. 7043-7048. [10.21873/anticanres.12175]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1483633
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