Introduction Nail diseases are often troubling to the patient and diagnostically challenging for dermatologists. Therefore, a nail biopsy is required in some cases although often perceived uncomfortable by the patient and potentially scarring. Non-invasive imaging techniques are of particular interest in the diagnosis of nail diseases, reducing the number of nail biopsies. Objective The main objective of this study was to describe the typical aspect of healthy nail in Dynamic OCT (D-OCT) and assess the morphological changes that occur in different affected nails. Secondary objective was to detect the main characteristics of each nail disease. Material and Methods This was an observational, retrospective study carried out in our dermatology center from January 2016 to June 2018. Consecutive patients affected by nail diseases and volunteers with healthy nail were recruited. There were no limitations in age or gender. Standardized clinical and dermoscopic images were acquired per patient. D-OCT (VivoSight®: Michelson Diagnostics, Maidstone, UK) was performed on the surface of any nail investigated at three different distances: proximal nail fold, proximal and distal part of the nail plate. In case of suspicious nail tumour, for a better identification of the lesion and its borders, more D-OCT acquisitions were executed. Results 25 nail diseases from 126 patients were evaluated and divided in six main groups: nail changes, ungual infections, ingrowing toenails, nail pigmentation, nail neoformations and inflammatory nail disorders. Mean age of our patient population was 45.7 years (range 9-87) and the majority were female (81 cases, 64.3%). Moreover, 2 healthy nails from 5 volunteers (2 men and 3 women) with a mean age of 34.4 years (range 26-56) were collected. Conclusions D-OCT allows an early diagnosis of nail disease, reduces the number of nail biopsies, helps for the biopsy site selection, detection of the nail tumours borders and for the treatment monitoring.
Role of dynamic optical coherence tomography for in vivo investigation of nails / Mandel, Victor Desmond; Starace, Michela; Piraccini, Bianca Maria; Pellacani, Giovanni. - (2019). (Intervento presentato al convegno 24th WCD tenutosi a Milano).
Role of dynamic optical coherence tomography for in vivo investigation of nails
PELLACANI, Giovanni
2019
Abstract
Introduction Nail diseases are often troubling to the patient and diagnostically challenging for dermatologists. Therefore, a nail biopsy is required in some cases although often perceived uncomfortable by the patient and potentially scarring. Non-invasive imaging techniques are of particular interest in the diagnosis of nail diseases, reducing the number of nail biopsies. Objective The main objective of this study was to describe the typical aspect of healthy nail in Dynamic OCT (D-OCT) and assess the morphological changes that occur in different affected nails. Secondary objective was to detect the main characteristics of each nail disease. Material and Methods This was an observational, retrospective study carried out in our dermatology center from January 2016 to June 2018. Consecutive patients affected by nail diseases and volunteers with healthy nail were recruited. There were no limitations in age or gender. Standardized clinical and dermoscopic images were acquired per patient. D-OCT (VivoSight®: Michelson Diagnostics, Maidstone, UK) was performed on the surface of any nail investigated at three different distances: proximal nail fold, proximal and distal part of the nail plate. In case of suspicious nail tumour, for a better identification of the lesion and its borders, more D-OCT acquisitions were executed. Results 25 nail diseases from 126 patients were evaluated and divided in six main groups: nail changes, ungual infections, ingrowing toenails, nail pigmentation, nail neoformations and inflammatory nail disorders. Mean age of our patient population was 45.7 years (range 9-87) and the majority were female (81 cases, 64.3%). Moreover, 2 healthy nails from 5 volunteers (2 men and 3 women) with a mean age of 34.4 years (range 26-56) were collected. Conclusions D-OCT allows an early diagnosis of nail disease, reduces the number of nail biopsies, helps for the biopsy site selection, detection of the nail tumours borders and for the treatment monitoring.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
