Background. Alcohol is a psychoactive substance with toxic and addictive properties. Biomarkers like GGT, AST, ALT and MCV are influenced by excessive ethanol consumption. Alcohol consumption represents a health risk and it has been linked to unemployment. The aim of this study how working status predict alcohol consumption through a cross sectional study comparing alcohol-related biomarkers levels in office workers and unemployed people. Methods. This study includes 157 office workers and 157 unemployed people, who were recruited from January to December 2018. A propensity score matching procedure was applied to obtain two homogenous groups in terms of age and gender. A non- parametric analysis was performed on serum biomarkers that are generally altered by alcohol consumption. Logistic regression models were designed to evaluate how working status predict abnormal biomarker levels related with alcohol consumption. Results. No differences in median biomarker values were found between groups. Lo- gistic regression analysis showed that office work is a negative predictor of pathological biomarker levels. Office workers had a significant relation with the levels of GGT (OR 0.48; 95% CI [0.28-0.84]), AST (OR 0.42; 95% CI [0.22-0.78]), ALT (OR 0.39; 95% CI [0.23-0.66]), and MCV (OR 0.37; 95% CI [0.19-0.70]). Conclusion. Office workers had lower absolute frequencies of pathological values of alcohol consumption biomarkers, after matching for age and gender compared with unemployed people. In addition, a significant negative association between office work is a negative predictor of biomarker levels of alcohol consumption. These results showed that work is an important determinant of health and that can represent a benefit for workers in terms of reducing the risk of consuming alcohol.

Alcohol consumption and employment: a cross-sectional study of office workers and unemployed people / De Sio, S.; Tittarelli, R.; Di Martino, G.; Buomprisco, G.; Perri, R.; Bruno, G.; Pantano, F.; Mannocchi, G.; Marinelli, E.; Cedrone, F.. - In: PEERJ. - ISSN 2167-8359. - 8:(2020), pp. 1-13. [10.7717/peerj.8774]

Alcohol consumption and employment: a cross-sectional study of office workers and unemployed people

De Sio S.
Primo
;
Tittarelli R.
Secondo
;
Buomprisco G.;Perri R.;Bruno G.;Pantano F.;Marinelli E.
Ultimo
;
2020

Abstract

Background. Alcohol is a psychoactive substance with toxic and addictive properties. Biomarkers like GGT, AST, ALT and MCV are influenced by excessive ethanol consumption. Alcohol consumption represents a health risk and it has been linked to unemployment. The aim of this study how working status predict alcohol consumption through a cross sectional study comparing alcohol-related biomarkers levels in office workers and unemployed people. Methods. This study includes 157 office workers and 157 unemployed people, who were recruited from January to December 2018. A propensity score matching procedure was applied to obtain two homogenous groups in terms of age and gender. A non- parametric analysis was performed on serum biomarkers that are generally altered by alcohol consumption. Logistic regression models were designed to evaluate how working status predict abnormal biomarker levels related with alcohol consumption. Results. No differences in median biomarker values were found between groups. Lo- gistic regression analysis showed that office work is a negative predictor of pathological biomarker levels. Office workers had a significant relation with the levels of GGT (OR 0.48; 95% CI [0.28-0.84]), AST (OR 0.42; 95% CI [0.22-0.78]), ALT (OR 0.39; 95% CI [0.23-0.66]), and MCV (OR 0.37; 95% CI [0.19-0.70]). Conclusion. Office workers had lower absolute frequencies of pathological values of alcohol consumption biomarkers, after matching for age and gender compared with unemployed people. In addition, a significant negative association between office work is a negative predictor of biomarker levels of alcohol consumption. These results showed that work is an important determinant of health and that can represent a benefit for workers in terms of reducing the risk of consuming alcohol.
alcohol consumption; office work; occupational medicine; alcohol and work
01 Pubblicazione su rivista::01a Articolo in rivista
Alcohol consumption and employment: a cross-sectional study of office workers and unemployed people / De Sio, S.; Tittarelli, R.; Di Martino, G.; Buomprisco, G.; Perri, R.; Bruno, G.; Pantano, F.; Mannocchi, G.; Marinelli, E.; Cedrone, F.. - In: PEERJ. - ISSN 2167-8359. - 8:(2020), pp. 1-13. [10.7717/peerj.8774]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1482777
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