Background: Bronchiolitis is the most common acute viral infection of the lower respiratory tract in infants. Clinical severity is associated with different risk factors; however, no clinical, laboratory, or radiological findings are able to predict the course of the disease in full-term infants. Lung ultrasound (LUS) is a valid technique for the diagnosis and evaluation of pediatric respiratory diseases. Aims: The aim of our study was to correlate an LUS score with a clinical score, to describe lung ultrasound findings in cases and controls, and to compare LUS findings with chest X-ray (CXR) in infants hospitalized with bronchiolitis. Methods: We conducted a single-center, longitudinal, prospective study on 92 infants. Sixty-three out of 92 infants were hospitalized for acute bronchiolitis (cases) and twenty-nine out of 92 for diseases not involving the respiratory system (controls). All patients with bronchiolitis underwent a clinical evaluation with the assignment of a clinical severity score and performed lung ultrasound with the assignment of an LUS score. Twenty-three out of 63 infants with bronchiolitis underwent also a CXR for clinical indications. Control infants performed only LUS. Results: In infants with bronchiolitis LUS score showed a positive correlation with the clinical score (r =.62, p <.001) and the length of hospitalization (r =.42; p <.001). The need of oxygen therapy was more frequent in the patients with higher LUS score (p <.001). LUS findings observed in the cases were the presence of B-lines, subpleural consolidations, and abnormalities of the pleural line. No LUS alterations were observed in the controls. In patients who performed LUS and CXR, we found a correlation between the presence of abnormalities of the pleural line with LUS and the presence of air trapping with CXR (r =.55; p =.007).

Lung ultrasound in bronchiolitis / La Regina, D.; Bloise, S.; Pepino, D.; Iovine, E.; Laudisa, M.; Cristiani, L.; Nicolai, A.; Nenna, R.; Mancino, E.; Di Mattia, G.; Petrarca, L.; Matera, L.; Frassanito, A.; Midulla, F.. - In: PEDIATRIC PULMONOLOGY. - ISSN 8755-6863. - 56:1(2020), pp. 234-239. [10.1002/ppul.25156]

Lung ultrasound in bronchiolitis

La Regina D.;Bloise S.;Pepino D.;Iovine E.;Laudisa M.;Cristiani L.;Nicolai A.;Nenna R.;Mancino E.;Di Mattia G.;Petrarca L.;Matera L.;Frassanito A.;Midulla F.
2020

Abstract

Background: Bronchiolitis is the most common acute viral infection of the lower respiratory tract in infants. Clinical severity is associated with different risk factors; however, no clinical, laboratory, or radiological findings are able to predict the course of the disease in full-term infants. Lung ultrasound (LUS) is a valid technique for the diagnosis and evaluation of pediatric respiratory diseases. Aims: The aim of our study was to correlate an LUS score with a clinical score, to describe lung ultrasound findings in cases and controls, and to compare LUS findings with chest X-ray (CXR) in infants hospitalized with bronchiolitis. Methods: We conducted a single-center, longitudinal, prospective study on 92 infants. Sixty-three out of 92 infants were hospitalized for acute bronchiolitis (cases) and twenty-nine out of 92 for diseases not involving the respiratory system (controls). All patients with bronchiolitis underwent a clinical evaluation with the assignment of a clinical severity score and performed lung ultrasound with the assignment of an LUS score. Twenty-three out of 63 infants with bronchiolitis underwent also a CXR for clinical indications. Control infants performed only LUS. Results: In infants with bronchiolitis LUS score showed a positive correlation with the clinical score (r =.62, p <.001) and the length of hospitalization (r =.42; p <.001). The need of oxygen therapy was more frequent in the patients with higher LUS score (p <.001). LUS findings observed in the cases were the presence of B-lines, subpleural consolidations, and abnormalities of the pleural line. No LUS alterations were observed in the controls. In patients who performed LUS and CXR, we found a correlation between the presence of abnormalities of the pleural line with LUS and the presence of air trapping with CXR (r =.55; p =.007).
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1476028
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