Sleep has a crucial role in memory processes, and maturational changes in sleep electrophysiology are involved in cognitive development. Albeit both sleep and memory alterations have been observed in Developmental Dyslexia (DD), their relation in this population has been scarcely investigated, particularly concerning topographical aspects. The study aimed to compare sleep topography and associated sleep-related declarative memory consolidation in participants with DD and normal readers (NR). Eleven participants with DD and 18 NR (9–14 years old) underwent a whole-night polysomnography. They were administered a word pair task before and after sleep to assess for declarative memory consolidation. Memory performance and sleep features (macro and microstructural) were compared between the groups, and the intercorrelations between consolidation rate and sleep measures were assessed. DD showed a deeper worsening in memory after sleep compared to NR and reduced slow spindles in occipito-parietal and left fronto-central areas. Our results suggest specific alterations in local sleep EEG (i.e., sleep spindles) and in sleep-dependent memory consolidation processes in DD.We highlight the importance of a topographical approach, which might shed light on potential alteration in regional cortical oscillation dynamics in DD. The latter might represent a target for therapeutic interventions aimed at enhancing cognitive functioning in DD.

Sleep-related declarative memory consolidation in children and adolescents with developmental dyslexia / Reda, Flaminia; Gorgoni, Maurizio; D'Atri, Aurora; Scarpelli, Serena; Carpi, Matteo; Di Cola, Erica; Menghini, Deny; Vicari, Stefano; Stella, Giacomo; De Gennaro, Luigi. - In: BRAIN SCIENCES. - ISSN 2076-3425. - 11:1(2021). [10.3390/brainsci11010073]

Sleep-related declarative memory consolidation in children and adolescents with developmental dyslexia

Reda, Flaminia;Gorgoni, Maurizio;D'Atri, Aurora;Scarpelli, Serena;Carpi, Matteo;De Gennaro, Luigi
2021

Abstract

Sleep has a crucial role in memory processes, and maturational changes in sleep electrophysiology are involved in cognitive development. Albeit both sleep and memory alterations have been observed in Developmental Dyslexia (DD), their relation in this population has been scarcely investigated, particularly concerning topographical aspects. The study aimed to compare sleep topography and associated sleep-related declarative memory consolidation in participants with DD and normal readers (NR). Eleven participants with DD and 18 NR (9–14 years old) underwent a whole-night polysomnography. They were administered a word pair task before and after sleep to assess for declarative memory consolidation. Memory performance and sleep features (macro and microstructural) were compared between the groups, and the intercorrelations between consolidation rate and sleep measures were assessed. DD showed a deeper worsening in memory after sleep compared to NR and reduced slow spindles in occipito-parietal and left fronto-central areas. Our results suggest specific alterations in local sleep EEG (i.e., sleep spindles) and in sleep-dependent memory consolidation processes in DD.We highlight the importance of a topographical approach, which might shed light on potential alteration in regional cortical oscillation dynamics in DD. The latter might represent a target for therapeutic interventions aimed at enhancing cognitive functioning in DD.
2021
developmental dyslexia; neurodevelopmental disorders; Non-Rapid Eye Movement (NREM) sleep; memory consolidation; sleep spindles; sleep oscillations; learning disabilities; predictive neurocognitive factors; slow wave activity; EEG topography
01 Pubblicazione su rivista::01a Articolo in rivista
Sleep-related declarative memory consolidation in children and adolescents with developmental dyslexia / Reda, Flaminia; Gorgoni, Maurizio; D'Atri, Aurora; Scarpelli, Serena; Carpi, Matteo; Di Cola, Erica; Menghini, Deny; Vicari, Stefano; Stella, Giacomo; De Gennaro, Luigi. - In: BRAIN SCIENCES. - ISSN 2076-3425. - 11:1(2021). [10.3390/brainsci11010073]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1473220
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