We retrospectively investigated, in 62 consecutive hospitalised COVID-19 patients (aged 70 ± 14 years, 40 males), the prognostic value of CT-derived subcutaneous adipose tissue and visceral adipose tissue (VAT) metrics, testing them in four predictive models for admission to intensive care unit (ICU), with and without pre-existing comorbidities. Multivariate logistic regression identified VAT score as the best ICU admission predictor (odds ratios 4.307-12.842). A non-relevant contribution of comorbidities at receiver operating characteristic analysis (area under the curve 0.821 for the CT-based model, 0.834 for the one including comorbidities) highlights the potential one-stop-shop prognostic role of CT-derived lung and adipose tissue metrics.

Visceral adipose tissue area predicts intensive care unit admission in COVID-19 patients / Pediconi, Federica; Rizzo, Veronica; Schiaffino, Simone; Cozzi, Andrea; Della Pepa, Gianmarco; Galati, Francesca; Catalano, Carlo; Sardanelli, Francesco. - In: OBESITY RESEARCH & CLINICAL PRACTICE. - ISSN 1871-403X. - (2020). [10.1016/j.orcp.2020.12.002]

Visceral adipose tissue area predicts intensive care unit admission in COVID-19 patients

Pediconi, Federica
Primo
;
Rizzo, Veronica
Secondo
;
Galati, Francesca;Catalano, Carlo
Penultimo
;
2020

Abstract

We retrospectively investigated, in 62 consecutive hospitalised COVID-19 patients (aged 70 ± 14 years, 40 males), the prognostic value of CT-derived subcutaneous adipose tissue and visceral adipose tissue (VAT) metrics, testing them in four predictive models for admission to intensive care unit (ICU), with and without pre-existing comorbidities. Multivariate logistic regression identified VAT score as the best ICU admission predictor (odds ratios 4.307-12.842). A non-relevant contribution of comorbidities at receiver operating characteristic analysis (area under the curve 0.821 for the CT-based model, 0.834 for the one including comorbidities) highlights the potential one-stop-shop prognostic role of CT-derived lung and adipose tissue metrics.
2020
COVID-19; critical care; intra-abdominal fat; severe acute respiratory syndrome coronavirus 2; subcutaneous fat; tomography, X-Ray computed
01 Pubblicazione su rivista::01a Articolo in rivista
Visceral adipose tissue area predicts intensive care unit admission in COVID-19 patients / Pediconi, Federica; Rizzo, Veronica; Schiaffino, Simone; Cozzi, Andrea; Della Pepa, Gianmarco; Galati, Francesca; Catalano, Carlo; Sardanelli, Francesco. - In: OBESITY RESEARCH & CLINICAL PRACTICE. - ISSN 1871-403X. - (2020). [10.1016/j.orcp.2020.12.002]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1472613
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