Uncertainties remain about the role of common thrombophilia markers as determinants of the ischemic stroke (IS) risk. Polymorphism His1299Arg in the FV gene, named R2 haplotype (FVHR2), has been poorly investigated. The aim of the present study was to assess the prevalence of common thrombophilia markers and of FVHR2 in a cohort of IS patients compared to a nonmatched group of healthy individuals.
Role of Factor V R2 Haplotype and Common Thrombophilia Markers as Genetic Risk Factors for Ischemic Stroke / Michele, Manuela De; Lorenzano, Svetlana; Angelosanto, Noemi; Serrao, Alessandra; Petraglia, Luca; Risitano, Angela; Toni, Danilo; Chistolini, Antonio. - In: JOURNAL OF STROKE MEDICINE. - ISSN 2516-6085. - 3:2(2020), pp. 144-150. [10.1177/2516608520973817]
Role of Factor V R2 Haplotype and Common Thrombophilia Markers as Genetic Risk Factors for Ischemic Stroke
Lorenzano, Svetlana;Angelosanto, Noemi;Serrao, Alessandra;Petraglia, Luca;Risitano, Angela;Toni, Danilo;Chistolini, Antonio
2020
Abstract
Uncertainties remain about the role of common thrombophilia markers as determinants of the ischemic stroke (IS) risk. Polymorphism His1299Arg in the FV gene, named R2 haplotype (FVHR2), has been poorly investigated. The aim of the present study was to assess the prevalence of common thrombophilia markers and of FVHR2 in a cohort of IS patients compared to a nonmatched group of healthy individuals.| File | Dimensione | Formato | |
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