At the nanoscale bone tissue is characterized by the mineralized collagen fibril (MCF), a recurring structure mainly composed of apatite mineral, tropocollagen molecules and water. The latter has a crucial role in bone biomineralization. In this study, we aim to analyse the mass transport at the collagen-apatite level of porosity by means of a 3D random walk model. We considered a representative building block of the MCF. The 3D random walk model is a valuable tool for investigating the influence of the structural hindrance on the diffusivity since the structure of the building block is included in the diffusion model.
Random Walk in 3D Model of Water Diffusion in the Human Mineralized Collagen Fibril ... in 2020 annual meeting of the american society for bone and mineral research virtual event September 11–15, 2020 / Bini, Fabiano; Pica, Andrada; Marinozzi, Andrea; Marinozzi, Franco. - In: JOURNAL OF BONE AND MINERAL RESEARCH. - ISSN 0884-0431. - 35:S1(2020), pp. 146-146. (Intervento presentato al convegno 2020 Annual Meeting of the American Society for Bone and Mineral Research tenutosi a Virtual Event) [10.1002/jbmr.4206].
Random Walk in 3D Model of Water Diffusion in the Human Mineralized Collagen Fibril ... in 2020 annual meeting of the american society for bone and mineral research virtual event September 11–15, 2020
Fabiano Bini
;Andrada Pica;Franco Marinozzi
2020
Abstract
At the nanoscale bone tissue is characterized by the mineralized collagen fibril (MCF), a recurring structure mainly composed of apatite mineral, tropocollagen molecules and water. The latter has a crucial role in bone biomineralization. In this study, we aim to analyse the mass transport at the collagen-apatite level of porosity by means of a 3D random walk model. We considered a representative building block of the MCF. The 3D random walk model is a valuable tool for investigating the influence of the structural hindrance on the diffusivity since the structure of the building block is included in the diffusion model.| File | Dimensione | Formato | |
|---|---|---|---|
|
Bini_Random-Walk_2020.pdf
accesso aperto
Note: frontespizio, indice e articolo
Tipologia:
Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza:
Tutti i diritti riservati (All rights reserved)
Dimensione
1.22 MB
Formato
Adobe PDF
|
1.22 MB | Adobe PDF |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
