Primates adopt various strategies to interact with the environment. Yet, no study has examined the effects of behavioural strategies with regard to how movement inhibition is implemented at the neuronal level. We used a modified version of the stop-task by adding an extra signal – termed the Ignore signal – capable of influencing the inhibition of movements only within a specific strategy. We simultaneously recorded multisite neuronal activity from the dorsal premotor (PMd) cortex of macaque monkeys during the task and applied a state-space approach. As a result, we found that movement generation is characterized by neuronal dynamics that evolve between subspaces. When the movement is halted, this evolution is arrested and inverted. Conversely, when the Ignore signal is presented, inversion of the evolution is observed briefly and only when a specific behavioural strategy is adopted. Moreover, neuronal signatures during the inhibitory process were predictive of how PMd processes inhibitory signals, allowing the classification of the resulting behavioural strategy. Our data further corroborate the PMd as a critical node in movement inhibition.

Neuronal dynamics of signal selective motor plan cancellation in the macaque dorsal premotor cortex / Giarrocco, F.; Bardella, G.; Giamundo, M.; Fabbrini, F.; Brunamonti, E.; Pani, P.; Ferraina, S.. - In: CORTEX. - ISSN 0010-9452. - 135:(2021), pp. 326-340. [10.1016/j.cortex.2020.09.032]

Neuronal dynamics of signal selective motor plan cancellation in the macaque dorsal premotor cortex

Giarrocco F.;Bardella G.;Giamundo M.;Brunamonti E.;Pani P.
;
Ferraina S.
2021

Abstract

Primates adopt various strategies to interact with the environment. Yet, no study has examined the effects of behavioural strategies with regard to how movement inhibition is implemented at the neuronal level. We used a modified version of the stop-task by adding an extra signal – termed the Ignore signal – capable of influencing the inhibition of movements only within a specific strategy. We simultaneously recorded multisite neuronal activity from the dorsal premotor (PMd) cortex of macaque monkeys during the task and applied a state-space approach. As a result, we found that movement generation is characterized by neuronal dynamics that evolve between subspaces. When the movement is halted, this evolution is arrested and inverted. Conversely, when the Ignore signal is presented, inversion of the evolution is observed briefly and only when a specific behavioural strategy is adopted. Moreover, neuronal signatures during the inhibitory process were predictive of how PMd processes inhibitory signals, allowing the classification of the resulting behavioural strategy. Our data further corroborate the PMd as a critical node in movement inhibition.
2021
Behavioural strategy; Dorsal premotor cortex; Neuronal activity; Selective inhibitory control
01 Pubblicazione su rivista::01a Articolo in rivista
Neuronal dynamics of signal selective motor plan cancellation in the macaque dorsal premotor cortex / Giarrocco, F.; Bardella, G.; Giamundo, M.; Fabbrini, F.; Brunamonti, E.; Pani, P.; Ferraina, S.. - In: CORTEX. - ISSN 0010-9452. - 135:(2021), pp. 326-340. [10.1016/j.cortex.2020.09.032]
File allegati a questo prodotto
File Dimensione Formato  
Giarrocco_Neuronal_2021.pdf

accesso aperto

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Creative commons
Dimensione 2.53 MB
Formato Adobe PDF
2.53 MB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1470694
Citazioni
  • ???jsp.display-item.citation.pmc??? 10
  • Scopus 16
  • ???jsp.display-item.citation.isi??? 15
social impact