Despite a massive body of knowledge which has been produced related to the mechanisms guiding muscle regeneration, great interest still moves the scientific community toward the study of different aspects of skeletal muscle homeostasis, plasticity, and regeneration. Indeed, the lack of effective therapies for several physiopathologic conditions suggests that a comprehensive knowledge of the different aspects of cellular behavior and molecular pathways, regulating each regenerative stage, has to be still devised. Hence, it is important to perform even more focused studies, taking the advantage of robust markers, reliable techniques, and reproducible protocols. Here, we provide an overview about the general aspects of muscle regeneration and discuss the different approaches to study the interrelated and time-dependent phases of muscle healing.

Mechanisms regulating muscle regeneration: insights into the interrelated and time-dependent phases of tissue healing / Forcina, L.; Cosentino, M.; Musaro', A.. - In: CELLS. - ISSN 2073-4409. - 9:5(2020), pp. 1-28. [10.3390/cells9051297]

Mechanisms regulating muscle regeneration: insights into the interrelated and time-dependent phases of tissue healing

Forcina L.;Cosentino M.;Musaro' A.
2020

Abstract

Despite a massive body of knowledge which has been produced related to the mechanisms guiding muscle regeneration, great interest still moves the scientific community toward the study of different aspects of skeletal muscle homeostasis, plasticity, and regeneration. Indeed, the lack of effective therapies for several physiopathologic conditions suggests that a comprehensive knowledge of the different aspects of cellular behavior and molecular pathways, regulating each regenerative stage, has to be still devised. Hence, it is important to perform even more focused studies, taking the advantage of robust markers, reliable techniques, and reproducible protocols. Here, we provide an overview about the general aspects of muscle regeneration and discuss the different approaches to study the interrelated and time-dependent phases of muscle healing.
2020
cell precursors; experimental methods; inflammatory response; muscle homeostasis; muscle regeneration; satellite cells; stem cell markers
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Mechanisms regulating muscle regeneration: insights into the interrelated and time-dependent phases of tissue healing / Forcina, L.; Cosentino, M.; Musaro', A.. - In: CELLS. - ISSN 2073-4409. - 9:5(2020), pp. 1-28. [10.3390/cells9051297]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1469101
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