Catalogo dei prodotti della ricerca

Dabigatran etexilate is a direct oral anticoagulant with potential to overcome the limitations of standard of care in children with venous thromboembolism. The aims of this clinical trial were to study the appropriateness of a paediatric dabigatran dosing algorithm, and the efficacy and safety of dabigatran dosed according to that algorithm versus standard of care in treating children with venous thromboembolism.

Dabigatran etexilate for the treatment of acute venous thromboembolism in children (DIVERSITY): a randomised, controlled, open-label, phase 2b/3, non-inferiority trial / Halton, Jacqueline; Brandão, Leonardo R; Luciani, Matteo; Bomgaars, Lisa; Chalmers, Elizabeth; Mitchell, Lesley G; Nurmeev, Ildar; Sharathkumar, Anjali; Svirin, Pavel; Gorbatikov, Kirill; Tartakovsky, Igor; Simetzberger, Monika; Huang, Fenglei; Sun, Zhichao; Kreuzer, Jörg; Gropper, Savion; Reilly, Paul; Brueckmann, Martina; Albisetti, Manuela; Nurmeev, Ildar; Safina, Asiya; Zapletal, Ondrej; Brandão, Leonardo R; Kuhn, Tomas; Votava, Tomas; Felgenhauer, Judy; Sharathkumar, Anjali; Svirin, Pavel; Amid, Ali; Halton, Jacqueline; Gorbatikov, Kirill; Saracco, Paola; Kiss, Csongor; Halimeh, Susan; Reschke, Madlen; Wulff, Beate; David, Michele; Novak, Zbynek; Trunina, Inna; Albisetti, Manuela; Frisk, Tony; Glosli, Heidi; Groll, Andreas; Lvova, Olga; Sasmaz, Ilgen; Sosothikul, Darintr; Zilinskaite, Virginija; Cockrell, Erin; Digtyar, Valeriy; Hadacova, Ivana; Palmu, Sauli; Pawar, Anjali; Annichino Bizzacchi, Joyce Maria; Caliskan, Umran; Celkan, Tiraje; Dmytriiev, Dmytro; Druzgal, Colleen Harkins; Onelda Elena, Graciela; Kattamis, Antonis; Kavakli, Ramazan Kaan; Male, Christoph; Ozdemir, Nihal; Van Damme, An; Zvereva, Tatiana; Aarli, Aanen; Paredes Aguilera, Rogelio Alejandro; Aytac, Selin; Carneiro, Jorge; Chistolini, Antonio; Mazzucconi, Maria Gabriela; Corrales-Medina, Fernando; Couturaud, Francis; Croteau, Stacey E; Trenor III, Cameron; Damgaard, Michael; Dixon, Natalia; Galustyan, Anna; Hak, Jiri; Hoffmann, Marianne; Kupesiz, Alphan; Labarque, Veerle; van Geet, Christel; Lin, Ming-Chih; Fu, Yun-Ching; Loggetto, Sandra; Mondelaers, Veerle; Odri-Komazec, Irena; Revel-Vilk, Shoshana; Sevilla, Julian; Fuzzato Silva, Luciano; Kerr Saraiva, José; Montes Tapia, Fernando Felix; Woods-Swafford, Wendy. - In: THE LANCET. HAEMATOLOGY. - ISSN 2352-3026. - (2020). [10.1016/S2352-3026(20)30368-9]

Dabigatran etexilate for the treatment of acute venous thromboembolism in children (DIVERSITY): a randomised, controlled, open-label, phase 2b/3, non-inferiority trial

Luciani, Matteo;Chistolini, Antonio;
2020

Abstract

Dabigatran etexilate is a direct oral anticoagulant with potential to overcome the limitations of standard of care in children with venous thromboembolism. The aims of this clinical trial were to study the appropriateness of a paediatric dabigatran dosing algorithm, and the efficacy and safety of dabigatran dosed according to that algorithm versus standard of care in treating children with venous thromboembolism.
2020
Dabigatran etexilate, acute venous thromboembolism, children
01 Pubblicazione su rivista::01a Articolo in rivista
Dabigatran etexilate for the treatment of acute venous thromboembolism in children (DIVERSITY): a randomised, controlled, open-label, phase 2b/3, non-inferiority trial / Halton, Jacqueline; Brandão, Leonardo R; Luciani, Matteo; Bomgaars, Lisa; Chalmers, Elizabeth; Mitchell, Lesley G; Nurmeev, Ildar; Sharathkumar, Anjali; Svirin, Pavel; Gorbatikov, Kirill; Tartakovsky, Igor; Simetzberger, Monika; Huang, Fenglei; Sun, Zhichao; Kreuzer, Jörg; Gropper, Savion; Reilly, Paul; Brueckmann, Martina; Albisetti, Manuela; Nurmeev, Ildar; Safina, Asiya; Zapletal, Ondrej; Brandão, Leonardo R; Kuhn, Tomas; Votava, Tomas; Felgenhauer, Judy; Sharathkumar, Anjali; Svirin, Pavel; Amid, Ali; Halton, Jacqueline; Gorbatikov, Kirill; Saracco, Paola; Kiss, Csongor; Halimeh, Susan; Reschke, Madlen; Wulff, Beate; David, Michele; Novak, Zbynek; Trunina, Inna; Albisetti, Manuela; Frisk, Tony; Glosli, Heidi; Groll, Andreas; Lvova, Olga; Sasmaz, Ilgen; Sosothikul, Darintr; Zilinskaite, Virginija; Cockrell, Erin; Digtyar, Valeriy; Hadacova, Ivana; Palmu, Sauli; Pawar, Anjali; Annichino Bizzacchi, Joyce Maria; Caliskan, Umran; Celkan, Tiraje; Dmytriiev, Dmytro; Druzgal, Colleen Harkins; Onelda Elena, Graciela; Kattamis, Antonis; Kavakli, Ramazan Kaan; Male, Christoph; Ozdemir, Nihal; Van Damme, An; Zvereva, Tatiana; Aarli, Aanen; Paredes Aguilera, Rogelio Alejandro; Aytac, Selin; Carneiro, Jorge; Chistolini, Antonio; Mazzucconi, Maria Gabriela; Corrales-Medina, Fernando; Couturaud, Francis; Croteau, Stacey E; Trenor III, Cameron; Damgaard, Michael; Dixon, Natalia; Galustyan, Anna; Hak, Jiri; Hoffmann, Marianne; Kupesiz, Alphan; Labarque, Veerle; van Geet, Christel; Lin, Ming-Chih; Fu, Yun-Ching; Loggetto, Sandra; Mondelaers, Veerle; Odri-Komazec, Irena; Revel-Vilk, Shoshana; Sevilla, Julian; Fuzzato Silva, Luciano; Kerr Saraiva, José; Montes Tapia, Fernando Felix; Woods-Swafford, Wendy. - In: THE LANCET. HAEMATOLOGY. - ISSN 2352-3026. - (2020). [10.1016/S2352-3026(20)30368-9]
01a Articolo in rivista
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1467769
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 136
  • ???jsp.display-item.citation.isi??? 117
social impact