Background and Objectives: In the last years, prepectoral breast reconstruction has increased its popularity, becoming a standard reconstructive technique by preserving pectoralis major anatomy and functionality. Nevertheless, the lack of solid and extensive data negatively impacts on surgeons’ correct information about postoperative complication rates and proper patient selection. This study aims to collect the largest evidence on this procedure. Methods: A multicentre retrospective audit, promoted by the Barcelona Hospital, collected the experience of 30 centers on prepectoral breast reconstruction with Braxon ADM. The study had the scientific support of INPECS and IIB societies which provided the online database Clinapsis. Results: A total of 1450 procedures were retrospectively collected in a 6-year period. Mean age 52.4 years, BMI 23.9, follow-up 22.7 months. Reconstruction was carried out after a tumor in 77.1% of the cases, 20.1% had prophylactic surgery, 2.8% had revisions. Diabetes, smoke, and immunosuppression had an influence on complications occurrence, as well as implant weight. Capsular contracture was associated with postoperative radiotherapy, but the overall rate was low (2.1%). Complications led to implant loss in 6.5% of the cases. Conclusions: The international Braxon Audit Group multicentre data collection represents a milestone in the field of breast reconstruction, extensively improving the knowledge on this procedure.

The largest multicentre data collection on prepectoral breast reconstruction: The iBAG study / Masia, J.; Salgarello, M.; Cattelani, L.; Parodi, P. C.; Ribuffo, D.; Onesti, M. G.; Berna, G.; Cawthorn, S. J.; Bozza, F.; Duodeci, S.; Harries, S.; Governa, M.; Barmasse, R. A.; Vidya, R.; Sircar, T.; Deol, H.; Guzzetti, T.; Meggiolaro, F.; Schiavon, M.; Parmeshwar, R.; Ferguson, D.; Mortimer, C.; Manca, G.; Thekkinkattil, D.; Rathinaezhil, R.; Bhaskar, P.; Roche, N.; Rivarossa, A.; De Castro Parga, G.; Massarut, S.; Polotto, S.; Di Bartolomeo, M.; Rampino Cordaro, E.; Mura, S.; Adesi, L. B.; Marruzzo, G.; Dell'Antonia, F.; Maritan, M.; Saibene, T.; Michieletto, S.; Cecconi, C.; Maino, M.; Clarke, D.; Mirandola, S.; Morelli, L.; Biral, M.; Baraziol, R.; Zanin, C.; Gregorelli, C.. - In: JOURNAL OF SURGICAL ONCOLOGY. - ISSN 0022-4790. - 122:5(2020), pp. 848-860. [10.1002/jso.26073]

The largest multicentre data collection on prepectoral breast reconstruction: The iBAG study

Ribuffo D.;Onesti M. G.;Mura S.;Marruzzo G.;Biral M.;
2020

Abstract

Background and Objectives: In the last years, prepectoral breast reconstruction has increased its popularity, becoming a standard reconstructive technique by preserving pectoralis major anatomy and functionality. Nevertheless, the lack of solid and extensive data negatively impacts on surgeons’ correct information about postoperative complication rates and proper patient selection. This study aims to collect the largest evidence on this procedure. Methods: A multicentre retrospective audit, promoted by the Barcelona Hospital, collected the experience of 30 centers on prepectoral breast reconstruction with Braxon ADM. The study had the scientific support of INPECS and IIB societies which provided the online database Clinapsis. Results: A total of 1450 procedures were retrospectively collected in a 6-year period. Mean age 52.4 years, BMI 23.9, follow-up 22.7 months. Reconstruction was carried out after a tumor in 77.1% of the cases, 20.1% had prophylactic surgery, 2.8% had revisions. Diabetes, smoke, and immunosuppression had an influence on complications occurrence, as well as implant weight. Capsular contracture was associated with postoperative radiotherapy, but the overall rate was low (2.1%). Complications led to implant loss in 6.5% of the cases. Conclusions: The international Braxon Audit Group multicentre data collection represents a milestone in the field of breast reconstruction, extensively improving the knowledge on this procedure.
2020
acellular dermal matrix; braxon; breast reconstruction; prepectoral; radiotherapy
01 Pubblicazione su rivista::01a Articolo in rivista
The largest multicentre data collection on prepectoral breast reconstruction: The iBAG study / Masia, J.; Salgarello, M.; Cattelani, L.; Parodi, P. C.; Ribuffo, D.; Onesti, M. G.; Berna, G.; Cawthorn, S. J.; Bozza, F.; Duodeci, S.; Harries, S.; Governa, M.; Barmasse, R. A.; Vidya, R.; Sircar, T.; Deol, H.; Guzzetti, T.; Meggiolaro, F.; Schiavon, M.; Parmeshwar, R.; Ferguson, D.; Mortimer, C.; Manca, G.; Thekkinkattil, D.; Rathinaezhil, R.; Bhaskar, P.; Roche, N.; Rivarossa, A.; De Castro Parga, G.; Massarut, S.; Polotto, S.; Di Bartolomeo, M.; Rampino Cordaro, E.; Mura, S.; Adesi, L. B.; Marruzzo, G.; Dell'Antonia, F.; Maritan, M.; Saibene, T.; Michieletto, S.; Cecconi, C.; Maino, M.; Clarke, D.; Mirandola, S.; Morelli, L.; Biral, M.; Baraziol, R.; Zanin, C.; Gregorelli, C.. - In: JOURNAL OF SURGICAL ONCOLOGY. - ISSN 0022-4790. - 122:5(2020), pp. 848-860. [10.1002/jso.26073]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1458256
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