Themost common subtype of renal cell carcinoma (RCC) is clear cell RCC (ccRCC) that accounts for 70–80% of all renal malignancies. To date, no useful markers are available in clinical practice for early diagnosis and for optimal patient stratification. MicroRNAs, a class of small non-coding RNA, are emerging as promising molecules in the management of urological tumors suggesting the possibility of using them as non-invasive biomarkers. The aim of this study is to evaluate whether miR-210-3p may be an accurate non invasive diagnostic and prognostic biomarker for ccRCC patients.
Liquid biopsy in clear cell renal cell carcinoma. Urinary miR-210-3p as emerging specific biomarker / Costantini, M.; Petrozza, V.; Tito, C.; Giammusso, L. M.; Sorrentino, V.; Cacciotti, J.; Porta, N.; Iaiza, A.; Pastore, A. L.; Di Carlo, A.; Simone, G.; Gallucci, M.; Carbone, A.; Fazi, F.. - In: EUROPEAN UROLOGY OPEN SCIENCE. - ISSN 2666-1691. - (2020). (Intervento presentato al convegno EAU Virtual Congress 2020 tenutosi a Online) [10.1016/S2666-1683(20)35516-6].
Liquid biopsy in clear cell renal cell carcinoma. Urinary miR-210-3p as emerging specific biomarker
V. Petrozza;C. Tito;V. Sorrentino;N. Porta;A. Iaiza;A. L. Pastore;A. Di Carlo;M. Gallucci;A. Carbone;F. Fazi
2020
Abstract
Themost common subtype of renal cell carcinoma (RCC) is clear cell RCC (ccRCC) that accounts for 70–80% of all renal malignancies. To date, no useful markers are available in clinical practice for early diagnosis and for optimal patient stratification. MicroRNAs, a class of small non-coding RNA, are emerging as promising molecules in the management of urological tumors suggesting the possibility of using them as non-invasive biomarkers. The aim of this study is to evaluate whether miR-210-3p may be an accurate non invasive diagnostic and prognostic biomarker for ccRCC patients.| File | Dimensione | Formato | |
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