There has been reported an increased melatonin secretion as an element of headache pathogenesis, perhaps related to the anti-inflammatory and analgesic effect of melatonin. The benefit of administered melatonin has been proved in adults affected by migraine, but it has never been tested in childhood. The aim of our study was to test the efficacy of melatonin therapy on the prevention of pediatric migraine. Despite the small number of participants, to our knowledge, this is the first study demonstrating the efficacy of melatonin treatment for prevention of childhood migraine and we confirmed the results of the similar study performed in adults. Controlled study in a large population of children is needed.
Melatonin, 3 mg, is an effective and alternative prophylactic treatment for headache prevention in a pediatric population / Miano, S; Parisi, Pasquale; Pelliccia, A; Luchetti, A; Paolino, MARIA CHIARA; Villa, MARIA PIA. - In: SLEEP MEDICINE. - ISSN 1389-9457. - STAMPA. - 8:Suppl. 1(2007), pp. 107-107. (Intervento presentato al convegno Second World Congress of Sleep Medicine tenutosi a Bangkok) [10.1016/S1389-9457(07)70406-9].
Melatonin, 3 mg, is an effective and alternative prophylactic treatment for headache prevention in a pediatric population
PARISI, Pasquale;PAOLINO, MARIA CHIARA;VILLA, MARIA PIA
2007
Abstract
There has been reported an increased melatonin secretion as an element of headache pathogenesis, perhaps related to the anti-inflammatory and analgesic effect of melatonin. The benefit of administered melatonin has been proved in adults affected by migraine, but it has never been tested in childhood. The aim of our study was to test the efficacy of melatonin therapy on the prevention of pediatric migraine. Despite the small number of participants, to our knowledge, this is the first study demonstrating the efficacy of melatonin treatment for prevention of childhood migraine and we confirmed the results of the similar study performed in adults. Controlled study in a large population of children is needed.File | Dimensione | Formato | |
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