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EnglishAims We evaluated the 1-year clinical events, pharmacological management, and quality of life in a contemporary cohort of stable coronary artery disease (CAD) patients managed by cardiologists.Methods and results START (STable Coronary Artery Diseases RegisTry) was a prospective, observational, nationwide study that enrolled 5070 stable CAD patients over 3 months in 183 cardiology centres in Italy. At 1 year, 4790 (94.5%) patients had data on vital status. Death occurred in 107 (2.2%) patients and the cause of death was cardiovascular in 41 (38.3%) of cases. Among the 4775 patients with follow-up data on clinical events available, a hospitalization due to cardiovascular and non-cardiovascular causes occurred in 523 (11.0%) and in 231 (4.8%) of cases, respectively. Over 60% of patients reported as 'no problems' in all domains (61.4-84.5%) of the EuroQoL quality of life 5D-5L questionnaire. Among the 3239 patients with clinical visit/telephone interview at follow-up, in whom optimal medical therapy (OMT; aspirin or thienopyridine, beta-blocker, and statin) was prescribed at enrolment, 2971 (91.7%) were still receiving OMT at follow-up. At multivariable analysis, only increasing age (odds ratio 0.98; 95% confidence interval 0.97-0.99; P = 0.04) resulted as independent negative predictor of OMT persistence at 1 year from enrolment.Conclusion In this large, contemporary registry, stable CAD patients managed by cardiologists presented a high rate of clinical events at 1 year. Nevertheless, the persistence to OMT and quality of life appeared reasonable.
Clinical outcomes, pharmacological treatment, and quality of life of patients with stable coronary artery diseases managed by cardiologists. 1-year results of the START study / Alessandri, Nicola. - In: EUROPEAN HEART JOURNAL. - ISSN 1522-9645. - 5:4(2019), pp. 334-342. [10.1093/ehjqcco/qcz002]
| Titolo: | Clinical outcomes, pharmacological treatment, and quality of life of patients with stable coronary artery diseases managed by cardiologists. 1-year results of the START study | |
| Autori: | ALESSANDRI, Nicola (Corresponding author) | |
| Data di pubblicazione: | 2019 | |
| Rivista: | ||
| Citazione: | Clinical outcomes, pharmacological treatment, and quality of life of patients with stable coronary artery diseases managed by cardiologists. 1-year results of the START study / Alessandri, Nicola. - In: EUROPEAN HEART JOURNAL. - ISSN 1522-9645. - 5:4(2019), pp. 334-342. [10.1093/ehjqcco/qcz002] | |
| Handle: | http://hdl.handle.net/11573/1445472 | |
| Appartiene alla tipologia: | 01a Articolo in rivista |
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