Benchmark performance of laparoscopic left lateral sectionectomy and right hepatectomy in expert centers

Hobeika, C.; Fuks, D.; Cauchy, F.; Goumard, C.; Gayet, B.; Laurent, A.; Soubrane, O.; Salame, E.; Cherqui, D.; Regimbeau, J. -M.; Mabrut, J. -Y.; Scatton, O.; Vibert, E.; Nomi, T.; Oudafal, N.; Kawai, T.; Komatsu, S.; Okumura, S.; Petrucciani, N.; Laurent, A.; Bucur, P.; Barbier, L.; Trechot, B.; Nunez, J.; Tedeschi, M.; Allard, M. -A.; Golse, N.; Ciacio, O.; Pittau, G.; Sa Cunha, A.; Adam, R.; Laurent, C.; Chiche, L.; Leourier, P.; Rebibo, L.; Regimbeau, J. -M.; Ferre, L.; Souche, F. R.; Chauvat, J.; Fabre, J. -M.; Jehaes, F.; Mohkam, K.; Lesurtel, M.; Ducerf, C.; Mabrut, J. -Y.; Hor, T.; Paye, F.; Balladur, P.; Suc, B.; Muscari, F.; Millet, G.; El Amrani, M.; Ratajczak, C.; Lecolle, K.; Boleslawski, E.; Truant, S.; Pruvot, F. -R.; Kianmanesh, A. -R.; Codjia, T.; Schwarz, L.; Girard, E.; Abba, J.; Letoublon, C.; Chirica, M.; Carmelo, A.; Vanbrugghe, C.; Cherkaoui, Z.; Unterteiner, X.; Memeo, R.; Pessaux, P.; Buc, E.; Lermite, E.; Barbieux, J.; Bougard, M.; Marchese, U.; Ewald, J.; Turini, O.; Thobie, A.; Menahem, B.; Mulliri, A.; Lubrano, J.; Zemour, J.; Fagot, H.; Passot, G.; Gregoire, E.; Hardwigsen, J.; le Treut, Y. -P.; Patrice, D.

doi:10.1016/j.jhep.2020.05.003

Background & Aims: Herein, we aimed to establish benchmark values – based on a composite indicator of healthcare quality – for the performance of laparoscopic left lateral sectionectomy (LLLS) and laparoscopic right hepatectomy (LRH) using data from expert centers. Methods: Data from a nationwide multicenter survey including all patients undergoing LLLS and LRH between 2000 and 2017 were analyzed. Textbook outcome (TO) completion was considered in patients fulfilling all 6 of the following characteristics: negative margins, no transfusion, no complication, no prolonged hospital stay, no readmission and no mortality. For each procedure, a cut-off laparoscopic liver resection (LLR) volume by center was associated with TO on multivariable analysis. These cut-offs defined the expert centers. The benchmark values were set at the 75th percentile of median outcomes among these expert centers. Results: Among 4,400 LLRs performed in 29 centers, 855 patients who underwent LLLS and 488 who underwent LRH were identified. The overall incidences of TO after LLLS and LRH were 43.7% and 23.8%, respectively. LLR volume cut-offs of 25 LLR/year (odds ratio [OR] 2.45; bootstrap 95% CI 1.65–3.69; p = 0.001) and 35 LLR/year (OR 2.55; bootstrap 95% CI 1.34–5.63; p = 0.003) were independently associated with completion of TO after LLLS and LRH, respectively. Eight centers for LLLS and 6 centers for LRH, including 516 and 346 patients undergoing LLLS/LRH respectively, reached these cut-offs and were identified as expert centers. After LLLS, benchmark values of severe complication, mortality and TO completion were defined as ≤5.3%, ≤1.2% and ≥46.6%, respectively. After LRH, benchmark values of severe complication, mortality and TO completion were ≤20.4%, ≤2.8% and ≥24.2%, respectively. Conclusions: This study provides an up-to-date reference on the benchmark performance of LLLS and LRH in expert centers. Lay summary: In a nationwide French survey of laparoscopic liver resection, expert centers were defined according to the completion of a textbook outcome, which is a composite indicator of healthcare quality. Benchmark values regarding intra-operative details and outcomes were established using data from 516 patients with laparoscopic left lateral sectionectiomy and 346 patients with laparoscopic right hepatectomy from expert centers. These values should be used as a reference point to improve the quality of laparoscopic resections.

Benchmark performance of laparoscopic left lateral sectionectomy and right hepatectomy in expert centers / Hobeika, C.; Fuks, D.; Cauchy, F.; Goumard, C.; Gayet, B.; Laurent, A.; Soubrane, O.; Salame, E.; Cherqui, D.; Regimbeau, J. -M.; Mabrut, J. -Y.; Scatton, O.; Vibert, E.; Nomi, T.; Oudafal, N.; Kawai, T.; Komatsu, S.; Okumura, S.; Petrucciani, N.; Laurent, A.; Bucur, P.; Barbier, L.; Trechot, B.; Nunez, J.; Tedeschi, M.; Allard, M. -A.; Golse, N.; Ciacio, O.; Pittau, G.; Sa Cunha, A.; Adam, R.; Laurent, C.; Chiche, L.; Leourier, P.; Rebibo, L.; Regimbeau, J. -M.; Ferre, L.; Souche, F. R.; Chauvat, J.; Fabre, J. -M.; Jehaes, F.; Mohkam, K.; Lesurtel, M.; Ducerf, C.; Mabrut, J. -Y.; Hor, T.; Paye, F.; Balladur, P.; Suc, B.; Muscari, F.; Millet, G.; El Amrani, M.; Ratajczak, C.; Lecolle, K.; Boleslawski, E.; Truant, S.; Pruvot, F. -R.; Kianmanesh, A. -R.; Codjia, T.; Schwarz, L.; Girard, E.; Abba, J.; Letoublon, C.; Chirica, M.; Carmelo, A.; VanBrugghe, C.; Cherkaoui, Z.; Unterteiner, X.; Memeo, R.; Pessaux, P.; Buc, E.; Lermite, E.; Barbieux, J.; Bougard, M.; Marchese, U.; Ewald, J.; Turini, O.; Thobie, A.; Menahem, B.; Mulliri, A.; Lubrano, J.; Zemour, J.; Fagot, H.; Passot, G.; Gregoire, E.; Hardwigsen, J.; le Treut, Y. -P.; Patrice, D.. - In: JOURNAL OF HEPATOLOGY. - ISSN 0168-8278. - (2020), pp. 1-9. [10.1016/j.jhep.2020.05.003]