OBJECTIVE 8 years follow-up (6.8 ± 2.2 years) of subjects with PFO. The evaluation of the incidence of cryptogenetic Stroke/TIA and/or migraine and/or platypnea-orthodoxy in subjects with PFO with and without closure. METHODS: 74 subjects were studied (17 M, 57 F), all originating from Latina and surrounding areas, with an average age of 50.3 ± 11.2 years; 56 patient were subjected to percutaneous closure for TIA/cryptogenetic stroke between the years 2008 and 2016. All patients under the same control protocol during the mean follow-up of 6.8 ± 2.2 years; RESULTS: there was no evidence of cerebrovascular recurrences in patients who had undergoing closure and in patients with medical prophylaxis. In 30/74 patients with migraine (with or without aurea), 13 sujects remained symptomatic after closure: 8 patients reported migraine with platypnea-orthodoxy, 2 patients symptoms free after closure. Two patients died > 12 months after the procedure from non-cardiovascular disease. CONCLUSION: Long-term follow-up, in a "selected" population for specific delivery from other medical centers, highlighted a high reduction (p< 0.01) in events associated with PFO with its closure. In the group undergoing percutaneous closure of the PFO, a significant reduction (p <0.001) of the incidence of cerebrovascular events (stroke / TIA) and (p <0.001) was observed in the reduction of other associations (migraine and / or platypse-orthodoxy ). Key words : PFO=Patent foramen ovale, SIA=Interatrial septal aneurysm, TIA=transient ischemic attack, TTE=transthoracic echocardiography, TEE=transesophageal echocardiography, DAPT=dual antiplatelet therapy
Long term follow-up in people with patent foramen ovale (PFO) / Alessandri, N.. - In: PARIPEX INDIAN JOURNAL OF RESEARCH. - ISSN 2250-1991. - 7:4(2018), pp. 37-41.
|Titolo:||Long term follow-up in people with patent foramen ovale (PFO)|
|Data di pubblicazione:||2018|
|Citazione:||Long term follow-up in people with patent foramen ovale (PFO) / Alessandri, N.. - In: PARIPEX INDIAN JOURNAL OF RESEARCH. - ISSN 2250-1991. - 7:4(2018), pp. 37-41.|
|Appartiene alla tipologia:||01a Articolo in rivista|