Unrevealing Takotsubo syndrome. appraising what has emerged from the International journal of cardiology contributions in 2019

Takotsubo Syndrome (TTS) has received much attention in recentyears because of its intriguing clinical presentation and pathophysiology [1]. It has been 27 years since Sato et al. described a clinical condition in which patients present with an abrupt angina-like chest pain and diffuse ST-segment changes in the absence of obstructive coronary artery disease (CAD) [1]. Although recent work has added several pieces to the complex puzzle of the pathophysiology of TTS (Fig. 1), multiple aspects remain unclear [2]. A number of articles published recently in the International Journal of Cardiology in 2019 have provided novel important contributions to our understanding of this condition.