Organocatalytic domino processes have become a rapidly growing area of research. N-heterocyclic carbenes (NHCs) have emerged as powerful organocatalysts for various transformations and continue to have widespread application. In the last decade, domino reactions catalyzed by NHCs have seen significant progress since the different activation modes could be successfully combined in one process. The most attractive features of these domino sequences include the readily available catalysts and substrates, the simple operational procedures, and the rapid assembly of complex molecular scaffolds with excellent levels of stereocontrol under mild reaction conditions. This review covers the advances in NHC-catalyzed domino reactions by focusing on the reaction scope, limitations, andmechanism with a close attention to the features of the reaction substrates.
N-heterocyclic-carbene-catalyzed domino reactions via two or more activation modes / Chen, Xiang-Yu; Li, Sun; Vetica, Fabrizio; Kumar, Mukesh; Enders, Dieter. - In: ISCIENCE. - ISSN 2589-0042. - 2(2018), pp. 1-26.
Titolo: | N-heterocyclic-carbene-catalyzed domino reactions via two or more activation modes | |
Autori: | ||
Data di pubblicazione: | 2018 | |
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Citazione: | N-heterocyclic-carbene-catalyzed domino reactions via two or more activation modes / Chen, Xiang-Yu; Li, Sun; Vetica, Fabrizio; Kumar, Mukesh; Enders, Dieter. - In: ISCIENCE. - ISSN 2589-0042. - 2(2018), pp. 1-26. | |
Handle: | http://hdl.handle.net/11573/1438024 | |
Appartiene alla tipologia: | 01g Articolo di rassegna (Review) |
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File | Note | Tipologia | Licenza | |
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Xiang-YuChen_N-Heterocyclic-Carbene-Catalyzed_2018.pdf | https://doi.org/10.1016/j.isci.2018.03.006 | Documento in Post-print (versione successiva alla peer review e accettata per la pubblicazione) | ![]() | Open Access Visualizza/Apri |