Recent advancement in the area of asymmetric organocatalysis led to the development of new methodologies for the construction of valuable enantiopure molecules, including various heterocycles. As one of the latter class of compounds tetrahydropyrans (THPs) constitute a core structure of a wide array of bioactive natural products. A noticeable growth has been observed in the asymmetric synthesis of THPs using small organic molecules as catalysts. This Tutorial Review describes the organocatalytic methods available to furnish THPs as well as the application of these methodologies in the total synthesis of THP-based natural products. © 2017 The Royal Society of Chemistry.
Asymmetric organocatalytic methods for the synthesis of tetrahydropyrans and their application in total synthesis / Vetica, Fabrizio; Chauhan, Pankaj; Dochain, Simon; Enders, Dieter. - In: CHEMICAL SOCIETY REVIEWS. - ISSN 0306-0012. - 46:6(2017), pp. 1661-1674. [10.1039/c6cs00757k]
Asymmetric organocatalytic methods for the synthesis of tetrahydropyrans and their application in total synthesis
Vetica, Fabrizio;
2017
Abstract
Recent advancement in the area of asymmetric organocatalysis led to the development of new methodologies for the construction of valuable enantiopure molecules, including various heterocycles. As one of the latter class of compounds tetrahydropyrans (THPs) constitute a core structure of a wide array of bioactive natural products. A noticeable growth has been observed in the asymmetric synthesis of THPs using small organic molecules as catalysts. This Tutorial Review describes the organocatalytic methods available to furnish THPs as well as the application of these methodologies in the total synthesis of THP-based natural products. © 2017 The Royal Society of Chemistry.File | Dimensione | Formato | |
---|---|---|---|
Vetica_Asymmetric_2017.pdf
solo gestori archivio
Tipologia:
Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza:
Tutti i diritti riservati (All rights reserved)
Dimensione
6.32 MB
Formato
Adobe PDF
|
6.32 MB | Adobe PDF | Contatta l'autore |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.