Langerhans Cell Histiocytosis is a rare hematologic disorder usually affecting children and most commonly involving the head and neck region. Primary oro-facial manifestations are rare, and their diagnosis is often challenging as they are numerous and often resemble common pathologies, refractory to conventional medical and/or instrumental treatments. For such reasons, the diagnosis is frequently delayed, as is the following staging and therapy onset. We retrospectively studied 45 pediatric patients affected by Langerhans Cell Histiocytosis with onset in the head and neck, to examine their clinical and radiological features at the early stage.
Primary oro-facial manifestations of Langerhans Cell Histiocytosis in pediatric age: A bi-Institutional retrospective study on 45 cases / Capodiferro, Saverio; Tempesta, Angela; Limongelli, Luisa; Ingravallo, Giuseppe; Maiorano, Eugenio; Sfasciotti, Gian Luca; Bossù, Maurizio; Polimeni, Antonella; Favia, Gianfranco. - In: CHILDREN. - ISSN 2227-9067. - 7:9(2020). [10.3390/children7090104]
Primary oro-facial manifestations of Langerhans Cell Histiocytosis in pediatric age: A bi-Institutional retrospective study on 45 cases
Sfasciotti, Gian Luca;Bossù, Maurizio;Polimeni, AntonellaPenultimo
;
2020
Abstract
Langerhans Cell Histiocytosis is a rare hematologic disorder usually affecting children and most commonly involving the head and neck region. Primary oro-facial manifestations are rare, and their diagnosis is often challenging as they are numerous and often resemble common pathologies, refractory to conventional medical and/or instrumental treatments. For such reasons, the diagnosis is frequently delayed, as is the following staging and therapy onset. We retrospectively studied 45 pediatric patients affected by Langerhans Cell Histiocytosis with onset in the head and neck, to examine their clinical and radiological features at the early stage.File | Dimensione | Formato | |
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