A methodol. has been developed for enantiodiscriminating chiral monoalcs. and monoamines by mass spectrometry. The approach is based on the generation of supersonically expanded complexes of these mols. with suitable chromophores, i.e. R-(+)-1-phenyl-ethanol (ER) or R-(+)-1-phenyl-1-propanol (PR). The jet-cooled diastereomeric complexes, otherwise elusive at room temp., have been ionized by one-color resonant two-photon absorption (R2PI) and their fragmentation pattern analyzed by time-of-flight (TOF) spectrometry. Enantiodifferentiation of the chiral monoalcs. and monoamines is based on: (1) the different spectral shifts of the band origin of their mol. complexes relative to that of the bare chromophore () and (2) the different mass spectral fragmentation patterns of the jet-cooled diastereomeric adducts. Detection of stable aggregates of methane, n-butane, and other simple mols. with the selected chromophores suggests that the R2PI/TOF method can be a potential tool for enantiodifferentiating chiral hydrocarbons in the gas phase.

Chiral Discrimination of Monofunctional Alcohols and Amines in the Gas Phase / Filippi, Antonello; Giardini, Anna; Latini, A; Piccirillo, S; Scuderi, D; Speranza, Maurizio. - In: INTERNATIONAL JOURNAL OF MASS SPECTROMETRY. - ISSN 1387-3806. - STAMPA. - 210/211:(2001), pp. 483-488.

Chiral Discrimination of Monofunctional Alcohols and Amines in the Gas Phase

FILIPPI, Antonello;GIARDINI, Anna;SPERANZA, Maurizio
2001

Abstract

A methodol. has been developed for enantiodiscriminating chiral monoalcs. and monoamines by mass spectrometry. The approach is based on the generation of supersonically expanded complexes of these mols. with suitable chromophores, i.e. R-(+)-1-phenyl-ethanol (ER) or R-(+)-1-phenyl-1-propanol (PR). The jet-cooled diastereomeric complexes, otherwise elusive at room temp., have been ionized by one-color resonant two-photon absorption (R2PI) and their fragmentation pattern analyzed by time-of-flight (TOF) spectrometry. Enantiodifferentiation of the chiral monoalcs. and monoamines is based on: (1) the different spectral shifts of the band origin of their mol. complexes relative to that of the bare chromophore () and (2) the different mass spectral fragmentation patterns of the jet-cooled diastereomeric adducts. Detection of stable aggregates of methane, n-butane, and other simple mols. with the selected chromophores suggests that the R2PI/TOF method can be a potential tool for enantiodifferentiating chiral hydrocarbons in the gas phase.
2001
01 Pubblicazione su rivista::01a Articolo in rivista
Chiral Discrimination of Monofunctional Alcohols and Amines in the Gas Phase / Filippi, Antonello; Giardini, Anna; Latini, A; Piccirillo, S; Scuderi, D; Speranza, Maurizio. - In: INTERNATIONAL JOURNAL OF MASS SPECTROMETRY. - ISSN 1387-3806. - STAMPA. - 210/211:(2001), pp. 483-488.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1435
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