Background: Aim of this study was to evaluate the impact of presurgical breast MRI on the surgical management of selected patients with early-stage breast cancer, who were candidates for BCT. Materials and methods: The trial was built up according to the major European Breast Society. In additional foci classified as BI-RADS 3-4 (4a, 4b, and 4c), a targeted second-look US study was performed. Results: A total of 123 patients underwent presurgical breast MRI. Therapeutic strategy established based on MRI was appropriate in 83.8% of cases. Analysis carried out on the subgroup of patients with dense breast showed that additional foci were found in 41.9% and a greater local extension of the index lesion in 6.4%. Conclusion: The results obtained in the subgroup of patients with high breast density suggest the importance of a sensitive tool such as MRI in the local staging of breast cancer before treatment planning.

The influence of preoperative MRI in early breast cancer: gold standard / Messineo, Daniela; Izzo, Luciano; Pisanelli, Massimo Codacci; Razionale, Francesco; Izzo, Sara; Izzo, Paolo. - In: ANNALI ITALIANI DI CHIRURGIA. - ISSN 2239-253X. - 91:(2020), pp. 144-153.

The influence of preoperative MRI in early breast cancer: gold standard

Messineo, Daniela
Primo
;
Izzo, Luciano
Secondo
;
Pisanelli, Massimo Codacci;Izzo, Sara;
2020

Abstract

Background: Aim of this study was to evaluate the impact of presurgical breast MRI on the surgical management of selected patients with early-stage breast cancer, who were candidates for BCT. Materials and methods: The trial was built up according to the major European Breast Society. In additional foci classified as BI-RADS 3-4 (4a, 4b, and 4c), a targeted second-look US study was performed. Results: A total of 123 patients underwent presurgical breast MRI. Therapeutic strategy established based on MRI was appropriate in 83.8% of cases. Analysis carried out on the subgroup of patients with dense breast showed that additional foci were found in 41.9% and a greater local extension of the index lesion in 6.4%. Conclusion: The results obtained in the subgroup of patients with high breast density suggest the importance of a sensitive tool such as MRI in the local staging of breast cancer before treatment planning.
2020
Breast cancer, BI-RADS, Histological diagnosis, Mammography MRI.
01 Pubblicazione su rivista::01a Articolo in rivista
The influence of preoperative MRI in early breast cancer: gold standard / Messineo, Daniela; Izzo, Luciano; Pisanelli, Massimo Codacci; Razionale, Francesco; Izzo, Sara; Izzo, Paolo. - In: ANNALI ITALIANI DI CHIRURGIA. - ISSN 2239-253X. - 91:(2020), pp. 144-153.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1433779
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