Background: The impact of seasonal changes on the incidence of acute myocardial infarction has been incompletely appraised, especially in the modern era of primary percutaneous coronary intervention (PPCI). We aimed to appraise the overall and season-specific impact of climate changes on the daily rate of PCCI. Methods: Details on PPCI and climate changes were retrospectively collected in three high-volume Italian institutions with different geographical features. The association between rate of PPCI and temperature, atmospheric pressure (ATM), humidity and rainfall was appraised with Poisson models, with overall analyses and according to season of the year. Results: Details on 6880 days with a total of 4132 PPCI were collected. Overall adjusted analysis showed that higher minimum atmospheric pressure 3 days before PPCI were associated with lower risk (regression coefficient = 0.999 [95% confidence interval 0.998–1.000], p = 0.030). Focusing on season, in Winter PPCI rates were increased by lower same day mean temperature (0.973 [0.956–0.990], p = 0.002) and lower rainfall (0.980 [0.960–1.000], p = 0.049). Conversely, in Spring greater changes in atmospheric pressure 3 days before PPCI were associated with increased risk (1.023 [1.002–1.045], p = 0.032), with similar effects in Summer for minimum temperature on the same day (1.022 [1.001–1.044], p = 0.040). Conclusions: Climate has a significant impact on the risk of PPCI in the current era, with a complex interplay according to season. Higher risk risk is expected with lower minimum atmospheric pressure in the preceding days, lower rainfall in Winter, greater changes in atmospheric pressure in Spring, and higher temperatures in Summer. These findings have important implications for prevention strategies.

Climate changes and ST-elevation myocardial infarction treated with primary percutaneous coronary angioplasty / Versaci, F.; Biondi-Zoccai, G.; Giudici, A. D.; Mariano, E.; Trivisonno, A.; Sciarretta, S.; Valenti, V.; Peruzzi, M.; Cavarretta, E.; Frati, G.; Scappaticci, M.; Federici, M.; Romeo, F.. - In: INTERNATIONAL JOURNAL OF CARDIOLOGY. - ISSN 0167-5273. - 294:(2019), pp. 1-5. [10.1016/j.ijcard.2019.07.006]

Climate changes and ST-elevation myocardial infarction treated with primary percutaneous coronary angioplasty

Biondi-Zoccai G.;Sciarretta S.;Valenti V.;Peruzzi M.;Cavarretta E.;Frati G.;
2019

Abstract

Background: The impact of seasonal changes on the incidence of acute myocardial infarction has been incompletely appraised, especially in the modern era of primary percutaneous coronary intervention (PPCI). We aimed to appraise the overall and season-specific impact of climate changes on the daily rate of PCCI. Methods: Details on PPCI and climate changes were retrospectively collected in three high-volume Italian institutions with different geographical features. The association between rate of PPCI and temperature, atmospheric pressure (ATM), humidity and rainfall was appraised with Poisson models, with overall analyses and according to season of the year. Results: Details on 6880 days with a total of 4132 PPCI were collected. Overall adjusted analysis showed that higher minimum atmospheric pressure 3 days before PPCI were associated with lower risk (regression coefficient = 0.999 [95% confidence interval 0.998–1.000], p = 0.030). Focusing on season, in Winter PPCI rates were increased by lower same day mean temperature (0.973 [0.956–0.990], p = 0.002) and lower rainfall (0.980 [0.960–1.000], p = 0.049). Conversely, in Spring greater changes in atmospheric pressure 3 days before PPCI were associated with increased risk (1.023 [1.002–1.045], p = 0.032), with similar effects in Summer for minimum temperature on the same day (1.022 [1.001–1.044], p = 0.040). Conclusions: Climate has a significant impact on the risk of PPCI in the current era, with a complex interplay according to season. Higher risk risk is expected with lower minimum atmospheric pressure in the preceding days, lower rainfall in Winter, greater changes in atmospheric pressure in Spring, and higher temperatures in Summer. These findings have important implications for prevention strategies.
2019
acute myocardial infarction; atherothrombosis; climate; coronary artery disease; primary percutaneous coronary intervention; aged; angioplasty, balloon, coronary; coronary angiography; female; humans; incidence; Italy; male; middle aged; percutaneous coronary intervention; retrospective studies; risk factors; ST elevation myocardial infarction; climate change; seasons
01 Pubblicazione su rivista::01a Articolo in rivista
Climate changes and ST-elevation myocardial infarction treated with primary percutaneous coronary angioplasty / Versaci, F.; Biondi-Zoccai, G.; Giudici, A. D.; Mariano, E.; Trivisonno, A.; Sciarretta, S.; Valenti, V.; Peruzzi, M.; Cavarretta, E.; Frati, G.; Scappaticci, M.; Federici, M.; Romeo, F.. - In: INTERNATIONAL JOURNAL OF CARDIOLOGY. - ISSN 0167-5273. - 294:(2019), pp. 1-5. [10.1016/j.ijcard.2019.07.006]
File allegati a questo prodotto
File Dimensione Formato  
Versaci_Climate-changes_2019.pdf

solo gestori archivio

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 244.32 kB
Formato Adobe PDF
244.32 kB Adobe PDF   Contatta l'autore

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1428934
Citazioni
  • ???jsp.display-item.citation.pmc??? 9
  • Scopus 25
  • ???jsp.display-item.citation.isi??? 24
social impact