Diabetic foot infections (DFIs) are severe complications of long-standing diabetes, and they represent a diagnostic challenge, since the differentiation between osteomyelitis (OM), soft tissue infection (STI), and Charcot's osteoarthropathy is very difficult to achieve. Nevertheless, such differential diagnosis is mandatory in order to plan the most appropriate treatment for the patient. The isolation of the pathogen from bone or soft tissues is still the gold standard for diagnosis; however, it would be desirable to have a non-invasive test that is able to detect, localize, and evaluate the extent of the infection with high accuracy. A multidisciplinary approach is the key for the correct management of diabetic patients dealing with infective complications, but at the moment, no definite diagnostic flow charts still exist. This review aims at providing an overview on multimodality imaging for the diagnosis of DFI and to address evidence-based answers to the clinicians when they appeal to radiologists or nuclear medicine (NM) physicians for studying their patients.

Diabetic Foot Infections. The Diagnostic Challenges / Lauri, Chiara; Leone, Antonio; Cavallini, Marco; Signore, Alberto; Giurato, Laura; Uccioli, Luigi. - In: JOURNAL OF CLINICAL MEDICINE. - ISSN 2077-0383. - 9:6(2020), pp. 1-20. [10.3390/jcm9061779]

Diabetic Foot Infections. The Diagnostic Challenges

Lauri, Chiara
Primo
Writing – Original Draft Preparation
;
Cavallini, Marco;Signore, Alberto;
2020

Abstract

Diabetic foot infections (DFIs) are severe complications of long-standing diabetes, and they represent a diagnostic challenge, since the differentiation between osteomyelitis (OM), soft tissue infection (STI), and Charcot's osteoarthropathy is very difficult to achieve. Nevertheless, such differential diagnosis is mandatory in order to plan the most appropriate treatment for the patient. The isolation of the pathogen from bone or soft tissues is still the gold standard for diagnosis; however, it would be desirable to have a non-invasive test that is able to detect, localize, and evaluate the extent of the infection with high accuracy. A multidisciplinary approach is the key for the correct management of diabetic patients dealing with infective complications, but at the moment, no definite diagnostic flow charts still exist. This review aims at providing an overview on multimodality imaging for the diagnosis of DFI and to address evidence-based answers to the clinicians when they appeal to radiologists or nuclear medicine (NM) physicians for studying their patients.
2020
mri; wbc scintigraphy; [18f]fdg pet/ct; diabetic foot; imaging; infection
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Diabetic Foot Infections. The Diagnostic Challenges / Lauri, Chiara; Leone, Antonio; Cavallini, Marco; Signore, Alberto; Giurato, Laura; Uccioli, Luigi. - In: JOURNAL OF CLINICAL MEDICINE. - ISSN 2077-0383. - 9:6(2020), pp. 1-20. [10.3390/jcm9061779]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1427368
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