Resveratrol has been widely studied for its therapeutic potential due to its antioxidant, anti-inflammatory and anti-microbial properties. In particular, resveratrol has shown promising antiviral activity against numerous viruses responsible for severe respiratory infections. Amongst these, influenza virus, respiratory syncytial virus and the emerging SARS-cov-2 are known to cause pneumonia, acute respiratory distress syndrome or multi-organ failure, especially, in vulnerable individuals like immunocompromised patients or the elderly, leading to a considerable economic burden worldwide. In this context, resveratrol may have potential value for its anti-inflammatory activity, since most of the severe virus-associated complications are related to the overactivation of the host-immune response, leading to lung damage. Herein, we present an overview of the antiviral activity and potential mechanisms of resveratrol against the respiratory tract viruses considered as a public threat for their rapid transmission and high morbidity and mortality in the general population.
Therapeutic potential of resveratrol against emerging respiratory viral infections / Filardo, S; Di Pietro, M; Mastromarino, P; Sessa, R. - In: PHARMACOLOGY & THERAPEUTICS. - ISSN 0163-7258. - (2020), pp. 1-9. [10.1016/j.pharmthera.2020.107613]
Titolo: | Therapeutic potential of resveratrol against emerging respiratory viral infections | |
Autori: | ||
Data di pubblicazione: | 2020 | |
Rivista: | ||
Citazione: | Therapeutic potential of resveratrol against emerging respiratory viral infections / Filardo, S; Di Pietro, M; Mastromarino, P; Sessa, R. - In: PHARMACOLOGY & THERAPEUTICS. - ISSN 0163-7258. - (2020), pp. 1-9. [10.1016/j.pharmthera.2020.107613] | |
Handle: | http://hdl.handle.net/11573/1427091 | |
Appartiene alla tipologia: | 01a Articolo in rivista |
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