Several nanotechnologies rely on the use of magnetic field for therapeutic purposes, as cancer treatment, inflammation, and diseases of the nervous system. The liposomal drug delivery system is a novel technique that allows a controlled release of drugs encapsulated in a nano-carrier (i.e. liposomes), by the application of an external (electric, magnetic, thermal) stimulus to guarantee a local effect on the region where the disease has developed. Another interesting application of magnetic field is the transcranial magnetic stimulation, which is used to the study and treatment of a wide variety of neurologic and psychiatric conditions. In this paper, an analytical analysis and a numeric modelling approach is reported for the design of a versatile magnetic exposure system, suitable for different applications: in vitro magnetoliposomes (vesicles containing super-paramagnetic iron oxide nanoparticles) drug delivery, and in vitro studies to understand the action of magnetic stimulation on neurons. The simulation shows that the system is able to generate intensities of the order of mT, in a frequency range up to 20 kHz, without causing secondary effects such as a local thermal increase.

Versatile exposure system for laboratory experiments finalized to therapeutic applications in the if range / Della Valle, E.; Camera, F.; Paffi, A.; Petralito, S.; Roncace, V.; Burattini, C.; Aicardi, G.; Liberti, M.; Apollonio, F.. - In: IEEE JOURNAL OF ELECTROMAGNETICS, RF AND MICROWAVES IN MEDICINE AND BIOLOGY.. - ISSN 2469-7249. - 2017-:(2017), pp. 1-4. (Intervento presentato al convegno 32nd General Assembly and Scientific Symposium of the International Union of Radio Science, URSI GASS 2017 tenutosi a Montréal) [10.23919/URSIGASS.2017.8105120].

Versatile exposure system for laboratory experiments finalized to therapeutic applications in the if range

Della Valle E.;Camera F.;Paffi A.;Petralito S.;Burattini C.;Aicardi G.;Liberti M.;Apollonio F.
2017

Abstract

Several nanotechnologies rely on the use of magnetic field for therapeutic purposes, as cancer treatment, inflammation, and diseases of the nervous system. The liposomal drug delivery system is a novel technique that allows a controlled release of drugs encapsulated in a nano-carrier (i.e. liposomes), by the application of an external (electric, magnetic, thermal) stimulus to guarantee a local effect on the region where the disease has developed. Another interesting application of magnetic field is the transcranial magnetic stimulation, which is used to the study and treatment of a wide variety of neurologic and psychiatric conditions. In this paper, an analytical analysis and a numeric modelling approach is reported for the design of a versatile magnetic exposure system, suitable for different applications: in vitro magnetoliposomes (vesicles containing super-paramagnetic iron oxide nanoparticles) drug delivery, and in vitro studies to understand the action of magnetic stimulation on neurons. The simulation shows that the system is able to generate intensities of the order of mT, in a frequency range up to 20 kHz, without causing secondary effects such as a local thermal increase.
2017
32nd General Assembly and Scientific Symposium of the International Union of Radio Science, URSI GASS 2017
magnetic stimulation; magnetoliposomes; bar codes; controlled drug delivery
04 Pubblicazione in atti di convegno::04h Atto di convegno in rivista scientifica o di classe A
Versatile exposure system for laboratory experiments finalized to therapeutic applications in the if range / Della Valle, E.; Camera, F.; Paffi, A.; Petralito, S.; Roncace, V.; Burattini, C.; Aicardi, G.; Liberti, M.; Apollonio, F.. - In: IEEE JOURNAL OF ELECTROMAGNETICS, RF AND MICROWAVES IN MEDICINE AND BIOLOGY.. - ISSN 2469-7249. - 2017-:(2017), pp. 1-4. (Intervento presentato al convegno 32nd General Assembly and Scientific Symposium of the International Union of Radio Science, URSI GASS 2017 tenutosi a Montréal) [10.23919/URSIGASS.2017.8105120].
File allegati a questo prodotto
File Dimensione Formato  
DellaValle_preprint_Versatile_2017.pdf

solo gestori archivio

Tipologia: Documento in Pre-print (manoscritto inviato all'editore, precedente alla peer review)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 1.07 MB
Formato Adobe PDF
1.07 MB Adobe PDF   Contatta l'autore
DellaValle_Versatile_2017.pdf

solo gestori archivio

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 524.04 kB
Formato Adobe PDF
524.04 kB Adobe PDF   Contatta l'autore

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1422696
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 1
  • ???jsp.display-item.citation.isi??? 1
social impact