Aspartate aminotransferase activity in peri-implant mucositis: experimental peri-implant mucositis model of 14 days

BACKGROUND: Experimental pen-implant mucositis has been studied from various prospective in a duration of 21 days. Given the higher sensitivity of pen-implant mucosa the aim of the present study was to evaluate if a duration of 14 days would be sufficient to establish a state of measurable inflammation. METHODS: Twenty patients of age 57 11-year-old contributed with 20 clinically healthy implants and teeth. They were instructed to use an individual stent in the selected elements prior to performing oral hygiene for 14 days. For each element plaque index (P11), probing depth (PD), bleeding on probing (Bops) were reported at 0 days and 14 days of plaque accumulation. Aspartate aminotransferase activity was measure at both time points from the crevicular fluid. RESULTS: Both implant and teeth developed similar increased response of inflammation at 14 days compared to day 0: BoPs of 4.2+1.8 (P 0.06) and BoPs of 3.1+2.2 (P 0.048) for implant and tooth, respectively. Implant presented deeper pocket depth at both time periods but less plaque accumulation. AST activity did not increased significantly, but it was significantly higher at implant level.