Many studies have focused on the relationship between hearing loss and Alzheimer's Disease (AD). The mechanisms and causal relationship of this association are still partially unknown, and several theories have been proposed. The most accredited hypothesis is that peripheral hearing deprivation may lead to social isolation and subsequently to dementia. Another hypothesis supports the role of hearing loss on cortical processing, with an increased assignment of cognitive resources to auditory processing rather than to other cognitive processes; other theories suggest changes in the brain structure following reduced peripheral auditory stimulation, or a common cause to both conditions. These preliminary findings clearly delineate the importance of further research aimed at investigating hearing impairment in AD, to a) allow early detection of people with predisposition to AD, b) improve the quality of life in AD patients with hearing loss and c) possibly prevent the progression of the disease treating the hearing impairment. In this review paper, the authors discuss current evidence on the association between hearing impairment and dementia, the identification of peripheral and central auditory dysfunction in at-risk patients as a potential early indicator of incipient AD, and the clinical aspects and the management of patients with AD and hearing loss.

Hearing loss and Alzheimer's disease: a review / Ralli, M.; Gilardi, A.; Di Stadio, A.; Severini, C.; Salzano, F. A.; Greco, A.; de Vincentiis, M.. - In: THE INTERNATIONAL TINNITUS JOURNAL. - ISSN 0946-5448. - 23:2(2019), pp. 79-85. [10.5935/0946-5448.20190014]

Hearing loss and Alzheimer's disease: a review

Ralli M.
Primo
;
Gilardi A.
Secondo
;
Di Stadio A.;Severini C.;Greco A.
Penultimo
;
de Vincentiis M.
Ultimo
2019

Abstract

Many studies have focused on the relationship between hearing loss and Alzheimer's Disease (AD). The mechanisms and causal relationship of this association are still partially unknown, and several theories have been proposed. The most accredited hypothesis is that peripheral hearing deprivation may lead to social isolation and subsequently to dementia. Another hypothesis supports the role of hearing loss on cortical processing, with an increased assignment of cognitive resources to auditory processing rather than to other cognitive processes; other theories suggest changes in the brain structure following reduced peripheral auditory stimulation, or a common cause to both conditions. These preliminary findings clearly delineate the importance of further research aimed at investigating hearing impairment in AD, to a) allow early detection of people with predisposition to AD, b) improve the quality of life in AD patients with hearing loss and c) possibly prevent the progression of the disease treating the hearing impairment. In this review paper, the authors discuss current evidence on the association between hearing impairment and dementia, the identification of peripheral and central auditory dysfunction in at-risk patients as a potential early indicator of incipient AD, and the clinical aspects and the management of patients with AD and hearing loss.
2019
Alzheimer's disease; Dementia; Hearing loss; Presbycusis
01 Pubblicazione su rivista::01a Articolo in rivista
Hearing loss and Alzheimer's disease: a review / Ralli, M.; Gilardi, A.; Di Stadio, A.; Severini, C.; Salzano, F. A.; Greco, A.; de Vincentiis, M.. - In: THE INTERNATIONAL TINNITUS JOURNAL. - ISSN 0946-5448. - 23:2(2019), pp. 79-85. [10.5935/0946-5448.20190014]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1412785
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