The use of magnetic fields in therapeutic applications has considerably increased in recent years. In particular, many researchers have focused their attention on the use of low-intensity magnetic fields, either alone or in combination with nanoparticles for drug delivery systems in nanomedicine. Laboratory experiments aimed at defining in vitro and in vivo outcomes are required, and reliable low-intensity magnetic field exposure systems are needed. In the present study, we have performed the analytical and numerical design of a novel magnetic exposure system suitable for different biological applications, such as magnetoliposome drug delivery, ex vivo experiments on brain slices, and in vivo studies. This system is able to generate intensities of the order of mT in a frequency range from ELF to 20 kHz.
A versatile magnetic exposure system for in-vitro, ex-vivo, and in-vivo experiments ifnalized to therapeutic applications in the IF range / Della Valle, E.; Liberti, M.; Camera, F.; Paffi, A.; Petralito, S.; Roncace, V.; Burattini, C.; Aicardi, G.; Apollonio, F.. - In: IEEE JOURNAL OF ELECTROMAGNETICS, RF AND MICROWAVES IN MEDICINE AND BIOLOGY.. - ISSN 2469-7249. - 3:1(2019), pp. 9-16. [10.1109/JERM.2018.2887077]
A versatile magnetic exposure system for in-vitro, ex-vivo, and in-vivo experiments ifnalized to therapeutic applications in the IF range
Liberti M.Secondo
;Camera F.;Paffi A.;Petralito S.;Apollonio F.Ultimo
2019
Abstract
The use of magnetic fields in therapeutic applications has considerably increased in recent years. In particular, many researchers have focused their attention on the use of low-intensity magnetic fields, either alone or in combination with nanoparticles for drug delivery systems in nanomedicine. Laboratory experiments aimed at defining in vitro and in vivo outcomes are required, and reliable low-intensity magnetic field exposure systems are needed. In the present study, we have performed the analytical and numerical design of a novel magnetic exposure system suitable for different biological applications, such as magnetoliposome drug delivery, ex vivo experiments on brain slices, and in vivo studies. This system is able to generate intensities of the order of mT in a frequency range from ELF to 20 kHz.File | Dimensione | Formato | |
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