Statement of Purpose: Hydrogels represent suitable platforms that can be designed to mimic the extracellular matrix microenvironment, and control the biological response of stem cells. Precisely, physical, mechanical and superficial properties of hydrogels dictate the ability of stem cells to adhere, proliferate, and differentiate. Understanding the role of each parameter can be useful to fabricate hydrogels with a set of well-defined properties to exert a direct control over stem cells morphology, secretion of therapeutic factors, as well as gene expression [1].
Modulation of stem cell morphology and differentiation using a mussel-inspired gelatin-based hydrogels / Pacelli, S.; Modaresi, S.; Chakravarti, A. R.; Vergel, F. E.; Kurlbaum, C.; Fang, M.; Castanho, F.; Basu, S.; Pau, l. A.. - 40:(2019), p. 693. (Intervento presentato al convegno 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence tenutosi a Seattle, United States).
Modulation of stem cell morphology and differentiation using a mussel-inspired gelatin-based hydrogels
Pacelli S.;
2019
Abstract
Statement of Purpose: Hydrogels represent suitable platforms that can be designed to mimic the extracellular matrix microenvironment, and control the biological response of stem cells. Precisely, physical, mechanical and superficial properties of hydrogels dictate the ability of stem cells to adhere, proliferate, and differentiate. Understanding the role of each parameter can be useful to fabricate hydrogels with a set of well-defined properties to exert a direct control over stem cells morphology, secretion of therapeutic factors, as well as gene expression [1].I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
