Purpose of Review: The aim of this review is to determine, in the light of recent evidences, the role of lymphadenectomy in ovarian cancer. Recent Findings: The lymphadenectomy in ovarian neoplasms (LION) trial reports no better outcomes and higher complication and mortality rates associated with lymphadenectomy. Even if performed by expert hands, lymphadenectomy has a cost in terms of longer operative time, blood loss, higher rates of transfusions, and intensive unit care. Summary: If on the one hand retroperitoneal staging is not correlated to survival benefits both in early and advanced ovarian cancer, on the other hand it is associated with an increased surgery-related morbidity. Surgical treatment of isolated nodal recurrences seems to be feasible and associated with survival benefits.

Lymphadenectomy in ovarian cancer: is it still justified? / Benedetti Panici, P.; Giannini, A.; Fischetti, M.; Lecce, F.; Di Donato, V.. - In: CURRENT ONCOLOGY REPORTS. - ISSN 1523-3790. - 22:3(2020), pp. 1-5. [10.1007/s11912-020-0883-2]

Lymphadenectomy in ovarian cancer: is it still justified?

Benedetti Panici P.;Giannini A.;Lecce F.;Di Donato V.
2020

Abstract

Purpose of Review: The aim of this review is to determine, in the light of recent evidences, the role of lymphadenectomy in ovarian cancer. Recent Findings: The lymphadenectomy in ovarian neoplasms (LION) trial reports no better outcomes and higher complication and mortality rates associated with lymphadenectomy. Even if performed by expert hands, lymphadenectomy has a cost in terms of longer operative time, blood loss, higher rates of transfusions, and intensive unit care. Summary: If on the one hand retroperitoneal staging is not correlated to survival benefits both in early and advanced ovarian cancer, on the other hand it is associated with an increased surgery-related morbidity. Surgical treatment of isolated nodal recurrences seems to be feasible and associated with survival benefits.
2020
lymphadenectomy; nodal metastasis; nodal recurrences; ovarian cancer; prognostic factor; surgical-related morbidity
01 Pubblicazione su rivista::01a Articolo in rivista
Lymphadenectomy in ovarian cancer: is it still justified? / Benedetti Panici, P.; Giannini, A.; Fischetti, M.; Lecce, F.; Di Donato, V.. - In: CURRENT ONCOLOGY REPORTS. - ISSN 1523-3790. - 22:3(2020), pp. 1-5. [10.1007/s11912-020-0883-2]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1399163
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