Basal cell carcinoma (BCC) is the most frequent skin cancer and is characterized by slow growth, even if it can be locally invasive and rarely metastasizes. Many different phenotypic presentations and histopathologic subtypes have been described, and the current guidelines subdivide BCCs into low-risk (nodular and superficial) and high-risk subtypes (micronodular, infiltrating, and morphoeic BCC and those with squamous differentiation). Dermoscopy allows the identification of the features associated with these different subtypes. Compared with the low-risk forms of BCC, more aggressive ones tend to undergo more frequently incomplete surgical excision and perineural invasion, so the identification of these lesions before surgery is extremely important. The gold standard of treatment is surgery, particularly for the H region of the face and infiltrative lesions, but other options are available and selected according to many variables, including body area, age, comorbidities, and clinical, dermoscopic, and histopathological features of the lesion. Moreover, the possible complications of surgical approaches, namely healing defects, failure of skin grafts, and wound infection, should be considered. In this review we discuss the management of BCC localized on the face and scalp, according to the currently available treatment options.

Face and scalp basal cell carcinoma treatment. A review of the literature / Bernardini, N; Skroza, N; Zuber, S; Tolino, E; Balduzzi, V; Mambrin, A; Marchesiello, A; Anzalone, A; Colapietra, D; Proietti, I; Potenza, C. - In: ACTA DERMATOVENEROLOGICA CROATICA. - ISSN 1330-027X. - 27:1(2019), pp. 22-27.

Face and scalp basal cell carcinoma treatment. A review of the literature

Bernardini, N;Skroza, N
;
Zuber, S;Tolino, E;Balduzzi, V;Mambrin, A;Marchesiello, A;Anzalone, A;Colapietra, D;Proietti, I;Potenza, C
2019

Abstract

Basal cell carcinoma (BCC) is the most frequent skin cancer and is characterized by slow growth, even if it can be locally invasive and rarely metastasizes. Many different phenotypic presentations and histopathologic subtypes have been described, and the current guidelines subdivide BCCs into low-risk (nodular and superficial) and high-risk subtypes (micronodular, infiltrating, and morphoeic BCC and those with squamous differentiation). Dermoscopy allows the identification of the features associated with these different subtypes. Compared with the low-risk forms of BCC, more aggressive ones tend to undergo more frequently incomplete surgical excision and perineural invasion, so the identification of these lesions before surgery is extremely important. The gold standard of treatment is surgery, particularly for the H region of the face and infiltrative lesions, but other options are available and selected according to many variables, including body area, age, comorbidities, and clinical, dermoscopic, and histopathological features of the lesion. Moreover, the possible complications of surgical approaches, namely healing defects, failure of skin grafts, and wound infection, should be considered. In this review we discuss the management of BCC localized on the face and scalp, according to the currently available treatment options.
basal cell carcinoma; face; scalp; treatment
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Face and scalp basal cell carcinoma treatment. A review of the literature / Bernardini, N; Skroza, N; Zuber, S; Tolino, E; Balduzzi, V; Mambrin, A; Marchesiello, A; Anzalone, A; Colapietra, D; Proietti, I; Potenza, C. - In: ACTA DERMATOVENEROLOGICA CROATICA. - ISSN 1330-027X. - 27:1(2019), pp. 22-27.
File allegati a questo prodotto
File Dimensione Formato  
Bernardini_Face_2019.PDF

solo gestori archivio

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 148.58 kB
Formato Adobe PDF
148.58 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1393231
Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 4
  • ???jsp.display-item.citation.isi??? 4
social impact