Schinus molle (L.) is a dioecious plant of the Anacardiaceae family, originating in South America and currently widespread in many regions throughout the world. In this work leaf extracts and derived low-pressure column chromatography (LPCC) fractions of S. molle L. male and female plants were investigated for the antimicrobial activity. Leaf extracts were tested on microbes Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Enterococcus faecalis, Candida albicans and Bacillus subtilis. Furthermore, the extracts showing antimicrobial activity were fractionated by LPCC and the obtained fractions tested on the same microorganism strains. Positive fractions were investigated by gas-chromatography/mass spectrometry (GC-MS) and were seen to be rich in sesquiterpenes, sesquiterpenoids and other terpens. The obtained effects highlighted the antimicrobial properties of S. molle (L.) leaf compounds and revealed their importance as a source of bioactive molecules of potential pharmaceutical interest. To our knowledge, this is the first paper reporting investigations on the chemical composition of the extracts and derived positive fractions from Schinus molle (L.) plants grown in central Italy.

Antimicrobial testing of schinus molle (l.) leaf extracts and fractions followed by gc-ms investigation of biological active fractions / Turchetti, G.; Garzoli, S.; Masci, V. L.; Sabia, C.; Iseppi, R.; Giacomello, P.; Tiezzi, A.; Ovidi, E.. - In: MOLECULES. - ISSN 1420-3049. - 25:8(2020). [10.3390/molecules25081977]

Antimicrobial testing of schinus molle (l.) leaf extracts and fractions followed by gc-ms investigation of biological active fractions

Garzoli S.
;
Giacomello P.;
2020

Abstract

Schinus molle (L.) is a dioecious plant of the Anacardiaceae family, originating in South America and currently widespread in many regions throughout the world. In this work leaf extracts and derived low-pressure column chromatography (LPCC) fractions of S. molle L. male and female plants were investigated for the antimicrobial activity. Leaf extracts were tested on microbes Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Enterococcus faecalis, Candida albicans and Bacillus subtilis. Furthermore, the extracts showing antimicrobial activity were fractionated by LPCC and the obtained fractions tested on the same microorganism strains. Positive fractions were investigated by gas-chromatography/mass spectrometry (GC-MS) and were seen to be rich in sesquiterpenes, sesquiterpenoids and other terpens. The obtained effects highlighted the antimicrobial properties of S. molle (L.) leaf compounds and revealed their importance as a source of bioactive molecules of potential pharmaceutical interest. To our knowledge, this is the first paper reporting investigations on the chemical composition of the extracts and derived positive fractions from Schinus molle (L.) plants grown in central Italy.
anacardiaceae; antimicrobial; gas chromatography-mass spectrometry; low-pressure column chromatography; minimum inhibitory concentration; pepper tree; plant compounds
01 Pubblicazione su rivista::01a Articolo in rivista
Antimicrobial testing of schinus molle (l.) leaf extracts and fractions followed by gc-ms investigation of biological active fractions / Turchetti, G.; Garzoli, S.; Masci, V. L.; Sabia, C.; Iseppi, R.; Giacomello, P.; Tiezzi, A.; Ovidi, E.. - In: MOLECULES. - ISSN 1420-3049. - 25:8(2020). [10.3390/molecules25081977]
File allegati a questo prodotto
File Dimensione Formato  
Turchetti_Antimicrobial_2020.pdf

accesso aperto

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Creative commons
Dimensione 271.27 kB
Formato Adobe PDF
271.27 kB Adobe PDF Visualizza/Apri PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1392970
Citazioni
  • ???jsp.display-item.citation.pmc??? 3
  • Scopus 5
  • ???jsp.display-item.citation.isi??? 4
social impact