Endometriosis is a widespread multifactorial disease in which environmental, genetic, and epigenetic factors contribute to the phenotype. Single Nucleotide Polymorphisms (SNPs) in genes implicated in pivotal molecular mechanisms have been investigated as susceptible risk factors in distinct populations. Among these, Toll-like receptor 4 (TLR4) represents a good candidate due to its role in the immune/inflammatory response and endometriosis pathogenesis.
Tlr4 t399i polymorphism and endometriosis in a cohort of italian women / Marchionni, Enrica; Porpora, Maria Grazia; Megiorni, Francesca; Piacenti, Ilaria; Giovannetti, Agnese; Marchese, Cinzia; Benedetti Panici, Pierluigi; Pizzuti, Antonio. - In: DIAGNOSTICS. - ISSN 2075-4418. - 10:5(2020), pp. 1-11. [10.3390/diagnostics10050255]
Tlr4 t399i polymorphism and endometriosis in a cohort of italian women
Marchionni, Enrica;Porpora, Maria Grazia;Megiorni, Francesca;Piacenti, Ilaria;Giovannetti, Agnese;Marchese, Cinzia;Benedetti Panici, Pierluigi;Pizzuti, Antonio
2020
Abstract
Endometriosis is a widespread multifactorial disease in which environmental, genetic, and epigenetic factors contribute to the phenotype. Single Nucleotide Polymorphisms (SNPs) in genes implicated in pivotal molecular mechanisms have been investigated as susceptible risk factors in distinct populations. Among these, Toll-like receptor 4 (TLR4) represents a good candidate due to its role in the immune/inflammatory response and endometriosis pathogenesis.| File | Dimensione | Formato | |
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