A contig covering human chromosome 6p22 that consists of 134 YAC clones aligned based on the presence/absence of 52 DNA markers is presented. This contig overlaps with the 6p23 contig at its telomeric end and with the 6p21.3 contig at its centromeric end. The order of loci within the contig resolves the relative positions of several genetically mapped markers. Among the additional markers used here, there are eight novel PCR assays. The 12 known genes and anonymous ESTs located within the contig establish a first step toward a transcriptional map of this region. The instability of YAC clones observed during this work is also discussed.

Construction of a YAC contig spanning human chromosome 6p22 / Malaspina, P; Roetto, A; Trettel, Flavia; Jodice, C; Blasi, P; Frontali, M; Carella, M; Franco, B; Camaschella, C. AND NOVELLETTO A.. - In: GENOMICS. - ISSN 0888-7543. - STAMPA. - 36:(1996), pp. 399-407. [10.1006/geno.1996.0484]

Construction of a YAC contig spanning human chromosome 6p22.

TRETTEL, Flavia;
1996

Abstract

A contig covering human chromosome 6p22 that consists of 134 YAC clones aligned based on the presence/absence of 52 DNA markers is presented. This contig overlaps with the 6p23 contig at its telomeric end and with the 6p21.3 contig at its centromeric end. The order of loci within the contig resolves the relative positions of several genetically mapped markers. Among the additional markers used here, there are eight novel PCR assays. The 12 known genes and anonymous ESTs located within the contig establish a first step toward a transcriptional map of this region. The instability of YAC clones observed during this work is also discussed.
SEQUENCE TAGS ESTS, HUMAN GENOME, REPEAT POLYMORPHISM, HUMAN MHC, MAP, REGION, GENE, ASSIGNMENT, LOCUS, DNA
01 Pubblicazione su rivista::01a Articolo in rivista
Construction of a YAC contig spanning human chromosome 6p22 / Malaspina, P; Roetto, A; Trettel, Flavia; Jodice, C; Blasi, P; Frontali, M; Carella, M; Franco, B; Camaschella, C. AND NOVELLETTO A.. - In: GENOMICS. - ISSN 0888-7543. - STAMPA. - 36:(1996), pp. 399-407. [10.1006/geno.1996.0484]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/138595
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