Apelin, the endogenous ligand of the G protein-coupled APJ receptor, displays several activities on the cardiovascular system. Indeed, recent studies support the notion that the apelin/APJ system is involved in key mechanisms that are relevant to fluid homeostasis, blood pressure control and cardiac contractility. This paper reviews our current knowledge on the physiological properties and potential clinical significance of apelin and APJ receptor.
The apelin/APJ system. From vascular biology to heart failure / Francia, Pietro; Balla, Cristina; Paneni, Francesco; Volpe, Massimo. - In: HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION. - ISSN 1120-9879. - STAMPA. - 13:4(2006), pp. 159-162.
The apelin/APJ system. From vascular biology to heart failure
FRANCIA, Pietro;BALLA, CRISTINA;PANENI, FRANCESCO;VOLPE, Massimo
2006
Abstract
Apelin, the endogenous ligand of the G protein-coupled APJ receptor, displays several activities on the cardiovascular system. Indeed, recent studies support the notion that the apelin/APJ system is involved in key mechanisms that are relevant to fluid homeostasis, blood pressure control and cardiac contractility. This paper reviews our current knowledge on the physiological properties and potential clinical significance of apelin and APJ receptor.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
