Objectives: Despite the efforts to reduce the exposure to corrosive household products, caustic ingestion in children is currently a significant medical problem. The aims of the present study were to evaluate the clinical consequences of caustic ingestion and to identify prognostic factors that could concur in driving both diagnostic and therapeutic management. Methods: All consecutive children referred for ingestion of a caustic substance from June 2017 to June 2018 were enrolled. Medical records, laboratory and endoscopic findings were reviewed and analyzed. Results: We enrolled 44 children with caustic ingestion. Alkaline agents were ingested by 26/44 (59.1%) patients, while acid agents were ingested by 18/44 patients (40.9%). Alkaline rather than acid agents were associated with a worse endoscopic score (r:0.45) and a higher probability of early esophageal stricture occurrence (r:0.38). The specific risk of the presence of severe esophageal lesions rose progressively with increasing number of symptoms while no esophageal injury was found in asymptomatic patients. Conclusions: Our data suggest that endoscopic evaluation is mandatory in symptomatic patients to direct therapeutic management, but it could be avoided in asymptomatic patients after accidental ingestion, particularly if the ingestion is only suspected and patients have no oropharyngeal burns.

Caustic Ingestion in Children. One Year Experience in Three Italian Referral Centers / Di Nardo, Giovanni; Betalli, Pietro; Illiceto, Maria Teresa; Giannotti, Giulia; Martemucci, Luigi; Caruso, Flora; Lisi, Gabriele; Romano, Giusy; Villa, Maria Pia; Ziparo, Chiara; Pensabene, Licia; Vassallo, Francesca; Quitadamo, Paolo. - In: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. - ISSN 0277-2116. - Mar 5(2020), pp. 1-17. [10.1097/MPG.0000000000002685]

Caustic Ingestion in Children. One Year Experience in Three Italian Referral Centers

Di Nardo, Giovanni
Primo
Writing – Review & Editing
;
Villa, Maria Pia;Ziparo, Chiara;Vassallo, Francesca;
2020

Abstract

Objectives: Despite the efforts to reduce the exposure to corrosive household products, caustic ingestion in children is currently a significant medical problem. The aims of the present study were to evaluate the clinical consequences of caustic ingestion and to identify prognostic factors that could concur in driving both diagnostic and therapeutic management. Methods: All consecutive children referred for ingestion of a caustic substance from June 2017 to June 2018 were enrolled. Medical records, laboratory and endoscopic findings were reviewed and analyzed. Results: We enrolled 44 children with caustic ingestion. Alkaline agents were ingested by 26/44 (59.1%) patients, while acid agents were ingested by 18/44 patients (40.9%). Alkaline rather than acid agents were associated with a worse endoscopic score (r:0.45) and a higher probability of early esophageal stricture occurrence (r:0.38). The specific risk of the presence of severe esophageal lesions rose progressively with increasing number of symptoms while no esophageal injury was found in asymptomatic patients. Conclusions: Our data suggest that endoscopic evaluation is mandatory in symptomatic patients to direct therapeutic management, but it could be avoided in asymptomatic patients after accidental ingestion, particularly if the ingestion is only suspected and patients have no oropharyngeal burns.
2020
caustic ingestion; esophageal burns; children
01 Pubblicazione su rivista::01a Articolo in rivista
Caustic Ingestion in Children. One Year Experience in Three Italian Referral Centers / Di Nardo, Giovanni; Betalli, Pietro; Illiceto, Maria Teresa; Giannotti, Giulia; Martemucci, Luigi; Caruso, Flora; Lisi, Gabriele; Romano, Giusy; Villa, Maria Pia; Ziparo, Chiara; Pensabene, Licia; Vassallo, Francesca; Quitadamo, Paolo. - In: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. - ISSN 0277-2116. - Mar 5(2020), pp. 1-17. [10.1097/MPG.0000000000002685]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1373735
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