We report an experimental investigation of an all-DNA gel composed by tetra-functional DNA nanoparticles acting as network nodes and bi-functional ones acting as links. The DNA binding sequence is designed to generate at room and lower temperatures a persistent long-lived network. Exploiting ideas from DNA-nanotechnology, we implement in the binding base sequences an appropriate exchange reaction which allows links to swap, constantly retaining the total number of network links. The DNA gel is thus able to rearrange its topology at low temperature while preserving its fully-bonded configuration.

Cold-swappable DNA gels / Bomboi, Francesca; Caprara, Debora; FERNANDEZ CASTANON, Javier; Sciortino, Francesco. - In: NANOSCALE. - ISSN 2040-3372. - 11:19(2019), pp. 9691-9697. [10.1039/c9nr01156k]

Cold-swappable DNA gels

Francesca Bomboi;Debora Caprara;Javier Fernandez-Castanon;Francesco Sciortino
2019

Abstract

We report an experimental investigation of an all-DNA gel composed by tetra-functional DNA nanoparticles acting as network nodes and bi-functional ones acting as links. The DNA binding sequence is designed to generate at room and lower temperatures a persistent long-lived network. Exploiting ideas from DNA-nanotechnology, we implement in the binding base sequences an appropriate exchange reaction which allows links to swap, constantly retaining the total number of network links. The DNA gel is thus able to rearrange its topology at low temperature while preserving its fully-bonded configuration.
DNA-gels; nanostars; bond swap
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Cold-swappable DNA gels / Bomboi, Francesca; Caprara, Debora; FERNANDEZ CASTANON, Javier; Sciortino, Francesco. - In: NANOSCALE. - ISSN 2040-3372. - 11:19(2019), pp. 9691-9697. [10.1039/c9nr01156k]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1364615
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