Preliminary results of the influence of Schizophyllum commune polysaccharides on the inhibition of mycotoxin synthesis in Aspergillus flavus and Aspergillus carbonarius Jelena Loncar1,3, Slaven Zjalić1 , Paola Cescutti2 Alice Motola 3, Massimo Reverberi3 1) Department of Ecology, Aquaculture and Agriculture, University of Zadar, Mihovila Pavlinovića 1, 23 000 Zadar, Croatia 2) Department of Life Sciences, University of Trieste, Via Licio Giorgieri 1, 34127 Trieste, Italy 3) Department of Environmental Biology, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy Abstract There has been interest in the use of mushroom polysaccharides to control the synthesis of key mycotoxins in staple commodities. Tramesan(c), an exo-polysaccharide produced by Trametes versicolor, is among the most efficient and studied ones. The objective of the present study were to analyse the effects of secreted polysaccharides of Schizophyllum commune on production of aflatoxin B1 (AFB1) and ochratoxin A (OTA) produced by Aspergillus flavus and Aspergillus carbonarius respectively. Comparison of the effects of commercial schizophyllan and partialy purified S. commune polysaccharides indicated that the inhibition of AFB1 and OTA synthesis may be due to other types of polysaccharide(s) rather than schizophyllan. Preliminary results suggest that the mechanism of efficacy of the S. commune polysaccharides could be analogous to that found previously for Tramesan®, i.e., by enhancing the antioxidant response in the target fungal cells.

Mushroom exo-polysaccharides as control agents of aflatoxin and ochratoxin. A biosynthesis / Loncar, Jelena. - (2020 Feb 10).

Mushroom exo-polysaccharides as control agents of aflatoxin and ochratoxin. A biosynthesis

LONCAR, JELENA
10/02/2020

Abstract

Preliminary results of the influence of Schizophyllum commune polysaccharides on the inhibition of mycotoxin synthesis in Aspergillus flavus and Aspergillus carbonarius Jelena Loncar1,3, Slaven Zjalić1 , Paola Cescutti2 Alice Motola 3, Massimo Reverberi3 1) Department of Ecology, Aquaculture and Agriculture, University of Zadar, Mihovila Pavlinovića 1, 23 000 Zadar, Croatia 2) Department of Life Sciences, University of Trieste, Via Licio Giorgieri 1, 34127 Trieste, Italy 3) Department of Environmental Biology, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy Abstract There has been interest in the use of mushroom polysaccharides to control the synthesis of key mycotoxins in staple commodities. Tramesan(c), an exo-polysaccharide produced by Trametes versicolor, is among the most efficient and studied ones. The objective of the present study were to analyse the effects of secreted polysaccharides of Schizophyllum commune on production of aflatoxin B1 (AFB1) and ochratoxin A (OTA) produced by Aspergillus flavus and Aspergillus carbonarius respectively. Comparison of the effects of commercial schizophyllan and partialy purified S. commune polysaccharides indicated that the inhibition of AFB1 and OTA synthesis may be due to other types of polysaccharide(s) rather than schizophyllan. Preliminary results suggest that the mechanism of efficacy of the S. commune polysaccharides could be analogous to that found previously for Tramesan®, i.e., by enhancing the antioxidant response in the target fungal cells.
10-feb-2020
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1363158
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