Stereotactic radiosurgery (SRS) is currently the most common treatment for small-to medium-size vestibular schwannoma (VS). Despite favorable outcome, hearing deterioration still remains an underestimated problem, and the role of hearing rehabilitation is an underinvestigated topic. Among available technologies, cochlear implant (CI) should represent a valid alternative in sporadic VS with single-sided deafness and in neurofibromatosis (NF2) with bilateral profound hearing loss. A literature review of the current clinical data was performed searching scientific literature databases. From all of the articles found, 16 papers were selected. Forty-four subjects treated with radiosurgery (18 male, 19 female, and in 7 cases, sex were not specified; 43 NF2 and 1 sporadic VS) were included in the analysis. Epidemiological, clinical, tumor, treatment, and audiological data were collected. Clinical outcome at last follow-up showed an audiological improvement in 25 of the 44 patients. The audiological outcomewasunchangedin16cases.Audiologicaldeterioration wasrecordedin3cases.Severity ofNF2phenotype,longhistory of ipsilateral profound deafness before implantation, progressive tumor growth, and high radiation dose (20 and 40 Gy) were found in patients with a worst audiological outcome. Hearing rehabilitation can improve audiological results for VS patients following SRS in selected cases. Hearing rehabilitation with cochlear implant (CI) in SSD leads to partial restoration of binaural hearing with an improvement in speech comprehension in noise and in sound localization, and partial suppression of subjective incapacitating tinnitus. SRS followed by CI may represent in selected cases a potential emerging option in the management of these patients, aimed at improving their quality of life. Possible implications for the follow-up of these patients are still present, although partially resolved.

The emerging role of hearing loss rehabilitation in patients with vestibular schwannoma treated with gamma knife radiosurgery: literature review / Morselli, Carlotta; Boari, Nicola; Artico, Marco; Bailo, Michele; Piccioni, Lucia; Giallini, Ilaria; DE VINCENTIIS, Marco; Mortini, Pietro; Mancini, Patrizia. - In: NEUROSURGICAL REVIEW. - ISSN 0344-5607. - 2021 Feb;44(1):(2021), pp. 223-238. [10.1007/s10143-020-01257-8]

The emerging role of hearing loss rehabilitation in patients with vestibular schwannoma treated with gamma knife radiosurgery: literature review

Carlotta Morselli
Primo
;
Marco Artico;Ilaria Giallini;Marco de Vincentiis;Patrizia Mancini
Ultimo
2021

Abstract

Stereotactic radiosurgery (SRS) is currently the most common treatment for small-to medium-size vestibular schwannoma (VS). Despite favorable outcome, hearing deterioration still remains an underestimated problem, and the role of hearing rehabilitation is an underinvestigated topic. Among available technologies, cochlear implant (CI) should represent a valid alternative in sporadic VS with single-sided deafness and in neurofibromatosis (NF2) with bilateral profound hearing loss. A literature review of the current clinical data was performed searching scientific literature databases. From all of the articles found, 16 papers were selected. Forty-four subjects treated with radiosurgery (18 male, 19 female, and in 7 cases, sex were not specified; 43 NF2 and 1 sporadic VS) were included in the analysis. Epidemiological, clinical, tumor, treatment, and audiological data were collected. Clinical outcome at last follow-up showed an audiological improvement in 25 of the 44 patients. The audiological outcomewasunchangedin16cases.Audiologicaldeterioration wasrecordedin3cases.Severity ofNF2phenotype,longhistory of ipsilateral profound deafness before implantation, progressive tumor growth, and high radiation dose (20 and 40 Gy) were found in patients with a worst audiological outcome. Hearing rehabilitation can improve audiological results for VS patients following SRS in selected cases. Hearing rehabilitation with cochlear implant (CI) in SSD leads to partial restoration of binaural hearing with an improvement in speech comprehension in noise and in sound localization, and partial suppression of subjective incapacitating tinnitus. SRS followed by CI may represent in selected cases a potential emerging option in the management of these patients, aimed at improving their quality of life. Possible implications for the follow-up of these patients are still present, although partially resolved.
2021
vestibular schwannoma; hearing loss; stereotactic radiosurgery; gamma knife; cochlear implant; hearing restoration
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
The emerging role of hearing loss rehabilitation in patients with vestibular schwannoma treated with gamma knife radiosurgery: literature review / Morselli, Carlotta; Boari, Nicola; Artico, Marco; Bailo, Michele; Piccioni, Lucia; Giallini, Ilaria; DE VINCENTIIS, Marco; Mortini, Pietro; Mancini, Patrizia. - In: NEUROSURGICAL REVIEW. - ISSN 0344-5607. - 2021 Feb;44(1):(2021), pp. 223-238. [10.1007/s10143-020-01257-8]
File allegati a questo prodotto
File Dimensione Formato  
Morselli_The emerging role_2020.pdf

solo gestori archivio

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 497.59 kB
Formato Adobe PDF
497.59 kB Adobe PDF   Contatta l'autore
GKRS_PAPER_Literature review FINAL.pdf

accesso aperto

Tipologia: Documento in Pre-print (manoscritto inviato all'editore, precedente alla peer review)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 299.12 kB
Formato Adobe PDF
299.12 kB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1360157
Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 10
  • ???jsp.display-item.citation.isi??? 7
social impact