Expulsion leiomyoma can represent an emergency condition and may lead to severe vaginal hemorrhage with anemia and urgent hysterectomy. Among medical treatments used for leiomyoma, Selective progesterone receptor modulators (SPRM) and, in particular, Ulipristal Acetate (UPA) have been proved to be effective in the management of bleeding and myoma size reduction. However, to our knowledge, there are no cases reported in literature on the use of UPA used as ‘emergency’ medical therapy in patients with severe anemia and vaginal bleeding due to expulsion leiomyoma. In this paper we would report two cases of patients affected by expulsion myoma successfully treated with UPA with immediate resolution of vaginal bleeding and subsequent elective conservative treatment.

Efficacy of ulipristal acetate (UPA) for the treatment of expulsion uterine myomas: report of two cases / Palaia, I.; Del Negro, V.; Fracassi, A.; Schiavi, M.; Di Donato, V.; Fischetti, M.; Muzii, L.; Benedetti Panici, P.. - In: GYNECOLOGICAL ENDOCRINOLOGY. - ISSN 0951-3590. - (2019), pp. 1-2-2. [10.1080/09513590.2019.1707795]

Efficacy of ulipristal acetate (UPA) for the treatment of expulsion uterine myomas: report of two cases

Palaia I.;Del Negro V.;Fracassi A.;Schiavi M.;Di Donato V.;Fischetti M.;Muzii L.;Benedetti Panici P.
2019

Abstract

Expulsion leiomyoma can represent an emergency condition and may lead to severe vaginal hemorrhage with anemia and urgent hysterectomy. Among medical treatments used for leiomyoma, Selective progesterone receptor modulators (SPRM) and, in particular, Ulipristal Acetate (UPA) have been proved to be effective in the management of bleeding and myoma size reduction. However, to our knowledge, there are no cases reported in literature on the use of UPA used as ‘emergency’ medical therapy in patients with severe anemia and vaginal bleeding due to expulsion leiomyoma. In this paper we would report two cases of patients affected by expulsion myoma successfully treated with UPA with immediate resolution of vaginal bleeding and subsequent elective conservative treatment.
2019
anemization; emergency; hemorrhage; leiomyoma; Ulipristal acetate
01 Pubblicazione su rivista::01a Articolo in rivista
Efficacy of ulipristal acetate (UPA) for the treatment of expulsion uterine myomas: report of two cases / Palaia, I.; Del Negro, V.; Fracassi, A.; Schiavi, M.; Di Donato, V.; Fischetti, M.; Muzii, L.; Benedetti Panici, P.. - In: GYNECOLOGICAL ENDOCRINOLOGY. - ISSN 0951-3590. - (2019), pp. 1-2-2. [10.1080/09513590.2019.1707795]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1350670
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