Background: Medication-related osteonecrosis of the jaw (MRONJ) is still without consensus on a standard treatment since the first report in 2003. The clinical management of MRONJ is comprised of medical, surgical approach or combined. Objective: This study aims to present our treatment protocols of Photo-biomodulation (PBM) as an adjunct to the management of patients with MRONJ. Materials and methods: A multidiodic laser (Lumix C.P.S. Dental, FISIOLINE, Verduno, Cuneo, Italy) emitting 650nm, 810 nm, and 910 nm wavelengths simultaneously was used with power of 0.6W and spot diameter of 8 mm in scanning mode for 15mins (per session). After a confirmed diagnosis of MRONJ, PBM was applied in three different aspects with antibiotic coverage. In treatment modality (a), PBM (5 sessions per cycle) was applied as an analgesic and anti-inflammatory as the surgical approach was not feasible. In treatment modality (b), it was applied as an adjunct (4 sessions per cycle) to the surgical approach with L-Platelet-Rich Fibrin (PRF). In treatment modality (c), the PBM (8 sessions per cycle) was applied in patients with osteonecrosis and bone exposure to support spontaneous sequestration. Results: In modality A, a significant reduction of pain and inflammation was observed. In modality B, most of the patients showed complete healing after the surgical approach with L-PRF. In modality C, in some patients spontaneous sequestration occurred with complete healing without the need for surgical intervention. Conclusions: The utilization of PBM in different ways according to the patient clinical situation may be a promising adjunctive modality for treating this challenging disease.
Different protocols of photobiomodulation for medication-related osteonecrosis of the jaw / Mohsen, Ahmed; Tenore, Gianluca; Palaia, Gaspare; Montori, Alessandra; Rocchetti, Federica; Aprea, Leandra; DEL VECCHIO, Alessandro; Romeo, Umberto. - In: PHOTOMEDICINE AND LASER SURGERY. - ISSN 1549-5418. - 37:10(2019), pp. A-9-A-9. [10.1089/photob.2019.29013.abstracts]
Different protocols of photobiomodulation for medication-related osteonecrosis of the jaw
Mohsen Ahmed
Primo
;Tenore GianlucaSecondo
;Palaia Gaspare;Rocchetti Federica;Del Vecchio AlessandroPenultimo
;Romeo UmbertoUltimo
2019
Abstract
Background: Medication-related osteonecrosis of the jaw (MRONJ) is still without consensus on a standard treatment since the first report in 2003. The clinical management of MRONJ is comprised of medical, surgical approach or combined. Objective: This study aims to present our treatment protocols of Photo-biomodulation (PBM) as an adjunct to the management of patients with MRONJ. Materials and methods: A multidiodic laser (Lumix C.P.S. Dental, FISIOLINE, Verduno, Cuneo, Italy) emitting 650nm, 810 nm, and 910 nm wavelengths simultaneously was used with power of 0.6W and spot diameter of 8 mm in scanning mode for 15mins (per session). After a confirmed diagnosis of MRONJ, PBM was applied in three different aspects with antibiotic coverage. In treatment modality (a), PBM (5 sessions per cycle) was applied as an analgesic and anti-inflammatory as the surgical approach was not feasible. In treatment modality (b), it was applied as an adjunct (4 sessions per cycle) to the surgical approach with L-Platelet-Rich Fibrin (PRF). In treatment modality (c), the PBM (8 sessions per cycle) was applied in patients with osteonecrosis and bone exposure to support spontaneous sequestration. Results: In modality A, a significant reduction of pain and inflammation was observed. In modality B, most of the patients showed complete healing after the surgical approach with L-PRF. In modality C, in some patients spontaneous sequestration occurred with complete healing without the need for surgical intervention. Conclusions: The utilization of PBM in different ways according to the patient clinical situation may be a promising adjunctive modality for treating this challenging disease.File | Dimensione | Formato | |
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Note: https://www.liebertpub.com/doi/full/10.1089/photob.2019.29013.abstracts
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